Schizophrenia Clinical Trials

Showing 381-400 of 661 trials

Augmentation of Neuronal Network Plasticity in Schizophrenia

NCT03522220

Current pathophysiological models of schizophrenia focus on disconnectivity of distributed neuronal systems to explain the multitude of psychic symptoms. However, therapeutic strategies targeting this specific pathobiology are lacking. Our recent work provides strong evidence that complex video-game training interventions facilitate fronto-hippocampal structural and functional connectivity within 2 months in healthy subjects. The planned project transfers this knowledge into a training study in schizophrenic patients to counteract disease-related disconnectivity. Underlying mechanisms and behavioral effects are extensively parametrized by resting state functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), spectroscopy and clinical short- and long-term outcome.

SchizophreniaHealthy

Universitätsklinikum Hamburg-Eppendorf150 participantsStarted Sep 2016

Hamburg, Germany

COMPLETEDPHASE2

Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia

NCT01077700

This is an efficacy and safety study evaluating an experimental treatment for cognitive deficits in adults with schizophrenia.

Cognitive Deficits in Schizophrenia

AbbVie (prior sponsor, Abbott)214 participantsStarted Mar 2010

Anaheim, California, United States • Garden Grove, California, United States • National City, California, United States +21 more locations

Augmentation of Neuronal Network Plasticity in Schizophrenia

Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia

Related Searches

Berberine Effect on Cytokine, CRP, Metabolic Disturbance as an Adjunctive Therapy in Schizophrenia Patients

Optimization of Treatment and Management of Schizophrenia in Europe

Effects of Physical Activity in Psychosis

Folate Supplementation in Schizophrenia

Brain Circuits in Schizophrenia and Smoking

Pharmacokinetics and Safety Studies of Esomeprazole Use in Schizophrenia Patients

Integrated Metacognitive Therapy in First Episode Psychosis

Normal and Abnormal ERP During ToM and Emotional Conflicts in Schizophrenia

Transcranial Direct Current Stimulation for Hallucinations in First-Episode Schizophrenia

Improving Cognition in Schizophrenia Using tDCS

SCIT Versus TAR for Outpatients With Schizophrenia

Repetitive Transcranial Magnetic Stimulation for the Treatment of Negative Symptoms in Schizophrenia Patients.

Pilot Trial of Valproate as Adjunctive Treatment for Toxoplasma Gondii Infection in Early Course Schizophrenia

A Pilot Trial of Curcumin Effects on Cognition in Schizophrenia

Withania Somnifera: an Immunomodulator and Anti-inflammatory Agent for Schizophrenia

Neurophysiological Targets for Cognitive Training in Schizophrenia

Enhancing Cognitive Training Through Exercise After a First Schizophrenia Episode

Perceptual Deficits in Schizophrenia