Rheumatoid Arthritis Clinical Trials

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A Study of MB-CART19.1 Cellular Therapy for People With Central Nervous System Lymphoma (CNSL)

NCT07137494

This study will test whether MB-CART19.1 is a safe and effective treatment for central nervous system lymphoma (CNSL). This study will test different doses of MB-CART19.1 to find the highest dose that causes few or mild side effects in participants.

Primary Central Nervous System (CNS) LymphomaSecondary Central Nervous System Lymphoma

Memorial Sloan Kettering Cancer Center12 participantsStarted Aug 2025

Basking Ridge, New Jersey, United States • Middletown, New Jersey, United States • Montvale, New Jersey, United States +4 more locations

Not Yet RecruitingPhase 1

Sitagliptin in Recurrent/Progressive Grade 4 Glioma

NCT07541781

Sitagliptin, when combined with standard-of-care drug bevacizumab, is being tested to 1) find out if it is effective at treating gliomas that have returned or progressed after treatment, and 2) find out what the highest dose of sitagliptin is appropriate to give when combined with bevacizumab.

GliomaGlioblastomaRecurrent Glioma+2 more

Kailin Yang, MD, PhD45 participantsStarted May 2026

Iowa City, Iowa, United States

A Study of MB-CART19.1 Cellular Therapy for People With Central Nervous System Lymphoma (CNSL)

Sitagliptin in Recurrent/Progressive Grade 4 Glioma

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