Rheumatoid Arthritis Clinical Trials

Showing 32061-32080 of 47,334 trials

Leg Thermotherapy for Intermittent Claudication

NCT02770547

This study proposes to evaluate the potential of leg thermotherapy as a non-pharmacological intervention that could improve the mobility and exercise tolerance of patients with intermittent claudication. Thermotherapy is a simple, easily applicable therapy that enhances exercise tolerance in patients with chronic heart failure by improving peripheral vascular endothelial function.

Peripheral Artery Disease

Indiana University32 participantsStarted May 2016

Indianapolis, Indiana, United States • Indianapolis, Indiana, United States

COMPLETEDPhase 2

Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic Headache

NCT03974360

An exploratory open-label study of PPTH patients to study the efficacy and tolerability of erenumab in the prophylactic treatment of persistent headache attributed to mild traumatic injury to the head. Approximately 100 subjects will be included to erenumab 140 mg. Patients who have participated in study with prior provocation (Ethics Committee of the Capital Region of Denmark (H-1801147 and H-18050498) and who have consented to be contacted will primarily be included. The study will begin February 2019 and is expected to last one year. Patients responding to advertisement (see add) will be contacted by phone.

Post-Traumatic HeadacheMild Traumatic Brain InjuryPost-Concussion Syndrome

Danish Headache Center100 participantsStarted Apr 2019

Glostrup Municipality, Copenhagen, Denmark

COMPLETEDPhase 4

Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant

NCT01239472

Currently, acute kidney injury is diagnosed by increased serum creatinine. However, creatinine is not a reliable marker for acute changes in renal function. The biology of the renal graft is influenced by chemokines from reperfusion (just after the kidney transplant) and throughout its course, when acute and chronic inflammatory changes occurs. Moreover, the evaluation of changes in urinary cytokines reflects kidney interstitial patterns, and can predict renal function, acute rejection episodes and their response to treatment. Today there are several studies comparing the relative immunosuppression of renal function, but few noticed its relationship with cytokines and chemokines. Thus, we proposed studying the inflammatory consequences of early calcineurin inhibitors (ICN) withdrawing in transplant patients by urine analysis. Kidney biopsy was done before ICN withdrawn and replaced by everolimus (3 months after transplant), and 1 year after transplant.

Renal Transplant RejectionImmunosuppression

Andre Barreto Pereira30 participantsStarted Jan 2011

Belo Horizonte, Minas Gerais, Brazil

Leg Thermotherapy for Intermittent Claudication

Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic Headache

Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant

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