Rheumatoid Arthritis Clinical Trials

Showing 31101-31120 of 47,334 trials

The Role of Optic Nerve Sheath Fenestration in Leukemic Patients Having Increased Intracranial Pressure

NCT04431882

Optic nerve sheath fenestration (ONSF) first described by De Wecker in 1872 for the treatment of neuroretinitis. Since then, optic nerve sheath fenestration has become well established procedure for treatment of papilledema in medically uncontrolled patients of idiopathic intracranial hypertension.

Leukemic Patients With Increased Intracranial PressureOptic Nerve Sheath Fenestration

Alexandria University20 participantsStarted Jun 2019

Alexandria, Egypt

RECRUITINGPhase 1/2

Lenalidomide in Combination With R-DA-EPOCH in Patients With Untreated DLBCL With MYC Rearrangement

NCT04432714

The prognosis of DLBCL with MYC rearrangement is dismal. Previous study showed that lenalidomide in combination with R-CHOP showed promising therapeutic activity and that R-DA EPOCH was superior compared to R-CHOP regimen in this cohort of patients. The investigators therefore design this phase I/II study to investigate the safety and efficacy of lenalidomide in combination with R-DA EPOCH in patients with untreated MYC-rearranged DLBCL.

DLBCLUntreatedMYC Gene Rearrangement

The First Affiliated Hospital with Nanjing Medical University81 participantsStarted Jun 2020

Nanjing, Jiangsu, China

The Role of Optic Nerve Sheath Fenestration in Leukemic Patients Having Increased Intracranial Pressure

Lenalidomide in Combination With R-DA-EPOCH in Patients With Untreated DLBCL With MYC Rearrangement

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