Rheumatoid Arthritis Clinical Trials

Showing 29421-29440 of 47,334 trials

Randomized Trial of Crenolanib in Subjects With D842V Mutated GIST

NCT02847429

This is a multicenter, randomized, double-blinded, placebo-controlled, trial of oral crenolanib versus oral placebo in combination with best supportive care in subjects with advanced or metastatic GIST with a D842V mutation in the PDGFRA gene. Approximately 120 subjects will be randomized in a 2:1 ratio to receive either crenolanib 100 mg or matching placebo orally (PO) 3 times daily (TID) in combination with best supportive care.

GIST With D842V Mutated PDGFRA Gene

Arog Pharmaceuticals, Inc.120 participantsStarted Aug 2016

Santa Monica, California, United States • Miami, Florida, United States • Durham, North Carolina, United States +20 more locations

COMPLETEDPhase 2

A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb Ischemia

NCT02016755

The purpose of the study is to confirm the feasibility of study procedures and the tolerability of a new dose regimen of AMG0001 in subjects with Critical Limb Ischemia (CLI)

Critical Limb IschemiaVascular DiseasesPeripheral Arterial Disease

AnGes USA, Inc.10 participantsStarted Nov 2013

Lebanon, New Hampshire, United States

Randomized Trial of Crenolanib in Subjects With D842V Mutated GIST

A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb Ischemia

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