Rheumatoid Arthritis Clinical Trials

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JT001 (VV116) for the Early Treatment of COVID-19

NCT05242042

The purpose of this study is to evaluate the efficacy, safety and pharmacokinetics of JT001 (VV116) for the early Treatment of Coronavirus Disease 2019 (COVID-19) in participants with mild to moderate COVID-19, at high risk for progression to severe COVID-19, including death.

Mild to Moderate COVID-19

Shanghai JunTop Biosciences Co., LTD381 participantsStarted Jan 2022

Chongqing, Chongqing Municipality, China • Zhengzhou, Henan, China • Wuxi, Jiangsu, China +5 more locations

COMPLETEDNA

Oral Self Care Protocol and Oral Mucositis

NCT06049511

Objective: This study was conducted in order to examine the effect of oral self-care protocol based on Orem's Self-Care Deficiency Theory on oral mucositis and self-care agency. Method: This study was conducted as a randomized controlled trial between August 2021 and July 2022, patients with hematological malignancies receiving high-dose chemotherapy at the Izmir Ege University Faculty of Medicine Hospital and Izmir Training and Research Hospital. The sample of the study consisted of a total of 60 patients, including 30 application groups and 30 control groups, who met the inclusion criteria using the computer-based stratified randomization method. The study data were collected using "Patient Information Questionnaire," "WHO-Oral Mucositis Toxicity Scale," "Oral Assessment Guide," "Self-Care Agency Scale," "Data Collection Form Prepared According to Orem's Self-Care Deficiency Nursing Theory," "Oral Care Chart," and "Oral Cavity Photography." The oral self-care protocol, which includes training and oral care practices, was applied to the application group for 21 days from the beginning of chemotherapy treatment. The control group was not subjected to any oral care attempts by the researcher and received standard nursing care in the clinic. The data were evaluated by descriptive statistics, the Chi-square test, the Mann-Whitney U test, the Mc Ne-mar test, the Kappa compliance test, and the t test in dependent and independent groups. Keywords: chemotherapy; hematological malignancy; oral mucositis; oral self-care protocol; Orem's theory; self-care agency; nursing

Mucositis Oral

Ege University60 participantsStarted Aug 2021

Izmir, Bornova, Turkey (Türkiye)

JT001 (VV116) for the Early Treatment of COVID-19

Oral Self Care Protocol and Oral Mucositis

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