Rheumatoid Arthritis Clinical Trials in Los Angeles

Showing 1321-1340 of 3,190 trials

Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant

NCT04087720

The primary objective of this study is to evaluate the effect of pegloticase on the response rate of sustained serum uric acid (sUA) reduction to sUA \< 6 mg/dL during Month 6 of treatment.

Uncontrolled GoutKidney Transplant

Amgen20 participantsStarted Sep 2019

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Los Angeles, California, United States +5 more locations

COMPLETEDPhase 2< 1 mile

Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy

NCT03719690

An international, multicenter, open-label, 2 cohort, non-comparative, pivotal study evaluating the efficacy of tipifarnib in HRAS mutant HNSCC (AIM-HN). The first cohort will assess the objective response rate (ORR) of tipifarnib in subjects with HNSCC with HRAS mutations. The second study cohort, SEQ-HN, is an observational sub-study including HNSCC patients in whom HRAS mutations were not identified (wild type HRAS HNSCC) and who consent to provide first line outcome data and additional follow up.

HRAS Gene MutationHNSCC

Kura Oncology, Inc.296 participantsStarted Mar 2019

Los Angeles, California, United States • Los Angeles, California, United States • San Francisco, California, United States +99 more locations

Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant

Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy

Rheumatoid Arthritis Trials in Other Cities

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Social Influences on Sensorimotor Integration of Speech Production and Perception During Early Vocal Learning

Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy

Adolescent Responses to Varying Environments in Virtual Reality Simulations

Cellular Immunotherapy in Recipients of HLA-matched, Living Donor Kidney Transplants

Frailty in Individuals With Advanced Heart Failure Part 2

Efficacy and Safety Evaluation of Tavilermide Ophthalmic Solution for the Treatment of Dry Eye

Expanded Access Protocol of Teprotumumab (HZN-001) for Patients With Active Thyroid Eye Disease

A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors

Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma

Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma

A Study of B + L Ophthalmic Viscosurgical Device (OVD) CVisc50

Study of ALVR106 in Patients With Respiratory Viral Infections After Hematopoietic Cell and Solid Organ Transplant

Transvaginal Radiofrequency Ablation for Overactive Bladder

Phase 2 Spectra Study to Evaluate the Safety and Efficacy of OPL-0401 in Patients With Diabetic Retinopathy

Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy

Trial for Treatment Refractory Trigeminal Neuralgia

Psychotherapy for PTSD Among Veterans Also Receiving Drug or Alcohol Treatment

Other Conditions in Los Angeles