Rheumatoid Arthritis Clinical Trials in Houston

Showing 861-880 of 3,412 trials

Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies

NCT03217747

This phase I/II trial studies the side effects of avelumab when given in different combinations with utomilumab, anti-OX40 antibody PF-04518600, and radiation therapy in treating patients with malignancies that have spread to other places in the body (advanced). Immunotherapy with monoclonal antibodies, such as avelumab, utomilumab, and anti-OX40 antibody PF-04518600, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Radiation therapy uses high-energy rays to kill tumor cells and shrink tumors. It is not yet known how well avelumab works in combination with these other anti-cancer therapies in patients with advanced malignancies.

Advanced Malignant Solid NeoplasmCastration-Resistant Prostate CarcinomaMalignant Solid Neoplasm+7 more

M.D. Anderson Cancer Center173 participantsStarted Aug 2017

Houston, Texas, United States

TERMINATEDPhase 1< 1 mile

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

NCT04543188

First-in-human study to assess safety, tolerability, PK, and preliminary activity of PF-07284890 as a single agent and in combination with binimetinib in participants with BRAF V600-mutated advanced solid tumor malignancies with and without brain involvement.

Malignant MelanomaCarcinoma, Non-Small-Cell LungBrain Neoplasms, Primary+2 more

Pfizer65 participantsStarted Jan 2021

Duarte, California, United States • San Francisco, California, United States • Orlando, Florida, United States +42 more locations

Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Rheumatoid Arthritis Trials in Other Cities

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

Transcutaneous Vagus Nerve Stimulation for Attention and Memory

Trial of Indication-Based Transfusion of Red Blood Cells in ECMO

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

BI655130 (SPESOLIMAB) Induction Treatment in Patients With Moderate-to-severe Ulcerative Colitis

Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD)

Longitudinal Study of Mitochondrial Hepatopathies

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

Inappropriate Sinus Tachycardia Registry

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC

A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

PUSH-IT Continuing Enteral Feeds for Tracheostomy

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

Effectiveness and Safety of the Octave System for Lifting the Eyebrow and Improving the Appearance of the Face and Neck

Other Conditions in Houston