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Browse 492 clinical trials for ptsd. Find studies that match your criteria and connect with research centers.
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NCT06135064
This study will evaluate a new form of non-invasive deep brain therapy for individuals with post-traumatic stress disorder (PTSD). Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during psychophysical and physiological monitoring. A well-tolerated stimulation protocol will be selected for subsequent testing in a blinded randomized sham-controlled cross-over trial. The trial will evaluate brain target engagement using magnetic resonance imaging and numerical scales of PTSD, cognitive performance, and mood.
NCT06984198
Due to the political state of Syria, Jordan is experiencing a major increase in the number of Syrians seeking asylum each year, a quarter of which are children. The stressors these refugees are exposed to are described in three stages: (1) while in their country of origin; (2) during their escape to safety; and (3) when having to settle in a country of refuge. The available literature shows consistently increased levels of psychological morbidity among refugee children, especially post-traumatic stress disorder (PTSD). It is argued that mental health clinics could use creative art therapies as a means of reaching out to war refugees in their communities who may not respond to traditional therapy. The difference in effectiveness between art and sand-play therapy, two models of nonverbal psychosocial therapy, on Syrian refugee children with PTSD, will be evaluated using a pretest-posttest control group design with 90 preadolescents (ages 6-12) exhibiting PTSD. Children will be randomized into two experimental groups (n = 30 for each) to receive sandplay or art therapy for 12 weeks, while the control group (n = 30) will receive no formal treatment. The effectiveness of each form of therapy will be determined using a questionnaire and then compared within and between group(s). Further statistical analysis will be used to determine which therapy was more effective in mitigating PTSD.