Psoriasis Clinical Trials

Showing 721-740 of 888 trials

Photocil (Topical) for the Treatment of Psoriasis Vulgaris

NCT01916629

Photocil is a topical drug (cream) that selectively delivers Narrow Band - Ultraviolet B (NB-UVB) therapy when exposed to sunlight. Photocil is intended to help protect users from non-therapeutic Ultraviolet B (UVB) radiation while selectively passing wavelengths of light in the NB-UVB range with peak transmission of 308nm. The aim of the study is to assess the safety and efficacy of Photocil in the treatment of psoriasis

Psoriasis

Applied Biology, Inc.12 participantsStarted Aug 2013

Tucson, Arizona, United States

COMPLETEDPhase 2

AMG 714 20060349 Multiple Dose Study in Moderate to Severe Psoriasis Subjects

NCT00443326

Investigational drug AMG 714 will be given to 66 subjects with moderate to severe psoriasis to study safety, pharmacokinetics, and efficacy. Dose levels include 150mg and 300mg and will be given to each subject for a total of 6 doses. Each dose for each subject will be given once every 2 weeks. Subjects will followed for up to 300 days post the first dose of AMG 714.

Psoriasis

Amgen22 participantsStarted Mar 2007

COMPLETEDPhase 2

Multiple-dose Regimen Study to Assess Effect of 12 Months of Secukinumab Treatment on Skin Response and Biomarkers in Psoriasis Patients

NCT01537432

This study is designed to evaluate the proportion of patients achieving reversal of chronic plaque psoriasis at week 4 and 12 following multiple doses of secukinumab administered subcutaneously (sc) compared to placebo. Starting from week 13, all patients will receive multiple doses of secukinumab up to week 52 to study long term effects of secukinumab. Clinical endpoints including biomarker assessments, PASI, IGA and DLQI will be compared to better understand, why secukinumab may be effective in psoriasis patients.

Psoriasis, Plaque-type Psoriasis

Novartis Pharmaceuticals36 participantsStarted Jan 2012

Birmingham, Alabama, United States • Pasadena, California, United States • Indianapolis, Indiana, United States +9 more locations

Photocil (Topical) for the Treatment of Psoriasis Vulgaris

AMG 714 20060349 Multiple Dose Study in Moderate to Severe Psoriasis Subjects

Multiple-dose Regimen Study to Assess Effect of 12 Months of Secukinumab Treatment on Skin Response and Biomarkers in Psoriasis Patients

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Assessing the Efficacy and Safety of Metformin in Treatment of Moderate Psoriasis

Pilot Study Characterizing Adipose Tissue Leukocytes by Flow Cytometry/Microscopy in Lean, Obese and Psoriatic Subjects

Blue Light for Treating Psoriasis Vulgaris

Clinical Assessment and Psychosocial Impact of Psoriasis

Evaluate the Effect of Elimune Capsules

A Study of BMS-582949 in Patients With Moderate to Severe Plaque Psoriasis

Post Marketing Surveillance Study of Remicade in Patients With Chronic Inflammatory Diseases (P04840)

Tofacitinib Ointment For Chronic Plaque Psoriasis

Efficacy of Atorvastatin as Adjunctive Treatment for Chronic Plaque Type Psoriasis

Efficacy of AIN457 in Adults (18-65 Years) With Psoriatic Arthritis

Greek Study on Work Productivity and Sleep in Patients With Rheumatic Diseases Treated With Adalimumab

Effect of Vitamin D Supplementation on Metabolic Parameters of Patients With Psoriasis

Assessment of Long-Term Infliximab for Psoriasis (P05319)

National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study

Long Term Study to Evaluate Safety and Efficacy of M518101 in Subjects With Plaque Psoriasis

AIN457 Regimen Finding Study in Patients With Moderate to Severe Psoriasis

A Study to Evaluate Raptiva in Subjects With Chronic Moderate or Worse Plaque Psoriasis Who Have Had an Inadequate Response to an Anti-TNF Agent