Parkinson's Disease Clinical Trials

Showing 1141-1160 of 1,818 trials

Effects of Transcranial Direct Current Stimulation on Postural Control

NCT03759132

Parkinson's disease is a progressive, degenerative neurological disease associated with profound changes in the quality of life of its survivors. Recent evidence has demonstrated the potential use of transcranial direct current stimulation (tDCS) to modulate cerebral excitability and movement control in neurological chronic conditions. However, few studies have investigated the effects of tDCS on postural control in patients with Parkinson's disease. This study aims to investigate the effect of bihemispheric tDCS on postural control in people with Parkinson's disease. Participants will be randomized to receive a single session of anodal and sham bihemispheric tDCS (7 days between each type of stimulation). Primary clinical outcome (balance) will be collected before and immediately after tDCS. The data will be collected by a blind examiner to the treatment allocation.

Parkinson Disease

Universidade Federal do Piauí18 participantsStarted Dec 2018

Parnaíba, Piauí, Brazil

COMPLETEDPhase 1

Staccato Apomorphine Multi-dose PK and PD in Patients With Parkinson's Disease

NCT04157933

This study will be conducted in subjects with established Parkinson's disease in 2 parts. Part A will examine the tolerability, safety, and pharmacokinetics of AZ-009 dose escalation ; and Part B will assess the tolerability, safety, pharmacokinetics, and pharmacodynamics of AZ-009 compared with placebo in a crossover design

Parkinson's Disease

Alexza Pharmaceuticals, Inc.35 participantsStarted Oct 2019

Leiden, Netherlands

Effects of Transcranial Direct Current Stimulation on Postural Control

Staccato Apomorphine Multi-dose PK and PD in Patients With Parkinson's Disease

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