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Clareo Health | Pancreatic Cancer Clinical Trials in North Carolina | 62 Studies

Clinical Trials Pancreatic CancerNorth Carolina

Pancreatic Cancer Clinical Trials in North Carolina

Find 62 clinical trials for pancreatic cancer near North Carolina. Connect with research centers in your area.

All Pancreatic Cancer trials nationwide All trials in North Carolina

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 62 trials

CompletedGemcitabine and ON 01910.Na in Previously Untreated Metastatic Pancreatic CancerThe question being asked in this study is: Will patients with advanced pancreatic cancer live significantly longer if they are treated with a combination of Gemcitabine and ON…NCT01360853·La Jolla, California and 45 others

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Data from ClinicalTrials.govTerms

CompletedErlotinib and Gemcitabine With or Without Panitumumab in Treating Patients With Metastatic Pancreatic CancerRATIONALE: Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.NCT00550836·Aurora, Colorado and 261 others

TerminatedPhase 3 Trial of 90Y-Clivatuzumab Tetraxetan & Gemcitabine vs Placebo & Gemcitabine in Metastatic Pancreatic CancerThe is a double-blind, randomized phase 3 study of 90Y-clivatuzumab tetraxetan with low-dose gemcitabine, versus placebo and low-dose gemcitabine in metastatic pancreatic cancer…NCT01956812·Gilbert, Arizona and 63 others

RecruitingAutologous CAR-T Cells Targeting B7-H3 in PDACThe purpose of this gene therapy research study is to test the safety and tolerability of using a new treatment called autologous T lymphocyte chimeric antigen receptor cells…NCT06158139·Chapel Hill, North Carolina

CompletedhTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of RelapseThis is a Phase I, open label study to evaluate the safety, tolerability, and immunogenicity of INO-1400 or INO-1401 alone or in combination with INO-9012, delivered by…NCT02960594·Detroit, Michigan and 5 others

Not yet recruitingThe STRONG Nutrition Support Study for People With Pancreatic CancerThis single-center pilot randomized controlled trial evaluates the feasibility, acceptability, and preliminary effects of STRONG, a digital nutrition support app delivered…NCT07826780·Chapel Hill, North Carolina

TerminatedQUILT-3.010: A Study of Gemcitabine and Nab-paclitaxel With or Without NPC-1C to Treat Patients With Pancreatic CancerThis was a Phase 1/2 multi-institution prospective open label study in which subjects with metastatic, locally advanced unresectable or recurrent pancreatic cancer who previously…NCT01834235·San Francisco, California and 11 others

CompletedS0727 Gemcitabine Hydrochloride and Erlotinib Hydrochloride With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By SurgeryThis randomized phase I/II trial is studying the side effects and best dose of monoclonal antibody therapy when given together with gemcitabine hydrochloride and erlotinib…NCT00617708·Jonesboro, Arkansas and 145 others

RecruitingAPL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid TumorsTo assess: * efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET…NCT03175224·Los Angeles, California and 34 others

Active not recruitingNivolumab and Ipilimumab in Treating Patients With Rare TumorsThis phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors.NCT02834013·Birmingham, Alabama and 1006 others

CompletedOxaliplatin, Gemcitabine, Erlotinib, and Radiation Therapy in Treating Patients With Unresectable and/or Metastatic Pancreatic Cancer or Biliary Tract CancerRATIONALE: Drugs used in chemotherapy, such as oxaliplatin and gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping…NCT00266097·Chapel Hill, North Carolina

Not yet recruitingA Decision Support Tool for Pancreatic Cancer Screening -Aim 2Pancreatic cancer has a rising incidence and poor survival. Early detection in high-risk individuals may substantially improve outcomes.NCT07808671·Chapel Hill, North Carolina

RecruitingA Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and FatigueStudy to investigate the efficacy, safety and tolerability of systemic chemotherapy plus ponsegromab versus systemic chemotherapy plus placebo for the first-line treatment in…NCT06989437·Birmingham, Alabama and 222 others

RecruitingStudy to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC PatientsTNG462-C102 is a Phase 1/2, open-label, multicenter study designed to determine the safety, tolerability, PK, PD, and preliminary antineoplastic activity of oral TNG462 in…NCT06922591·Scottsdale, Arizona and 17 others

CompletedA Study of Napabucasin Plus Nab-Paclitaxel With Gemcitabine in Adult Patients With Metastatic Pancreatic AdenocarcinomaThis is a randomized, open-label, multi-center, phase 3 study of napabucasin plus weekly nab-paclitaxel with gemcitabine versus weekly nab-paclitaxel with gemcitabine for adult…NCT02993731·Birmingham, Alabama and 266 others

CompletedBKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic CancerThe purpose of this study is to establish the safety and tolerability of BKM120 when combined with mFOLFOX6 and to define the maximum tolerated dose of BKM120 in this combination…NCT01571024·Chapel Hill, North Carolina

Active not recruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)This phase II MATCH screening and multi-sub-trial studies how well treatment that is directed by genetic testing works in patients with solid tumors, lymphomas, or multiple…NCT02465060·Birmingham, Alabama and 1409 others

CompletedMobile Weight Loss Intervention for Adolescent and Young Adult Cancer SurvivorsThe purpose of this study is to conduct a 6-month pilot randomized trial to determine the feasibility and acceptability of theory-based mobile weight loss interventions for…NCT06171945·Chapel Hill, North Carolina

Active not recruitingStudy of JANX008 in Subjects With Advanced or Metastatic Solid Tumor MalignanciesThis study is a first-in-human (FIH), Phase 1/1b, open-label, multicenter dose escalation and dose expansion study to assess the safety, tolerability, pharmacokinetics (PK)…NCT05783622·Duarte, California and 17 others

Active not recruitingColorectal Cancer Screening in Cystic FibrosisThis multi-center study will compare multi-target DNA and quantitative FIT stool-based testing to colonoscopy in individuals with Cystic Fibrosis (CF) undergoing colon cancer…NCT05362344·Los Angeles, California and 25 others

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