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Clinical Trials Pancreatic CancerDenver

Pancreatic Cancer Clinical Trials in Denver

Find 129 clinical trials for pancreatic cancer near Denver, Colorado. Connect with research centers in your area.

All Pancreatic Cancer trials nationwide All trials in Denver

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 41-60 of 129 trials

Active not recruitingPhase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors that have a…NCT03785249·Birmingham, Alabama and 221 others

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Data from ClinicalTrials.govTerms

CompletedFOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic CancerThis randomized phase II trial studies how well modified irinotecan hydrochloride, leucovorin calcium, fluorouracil (FOLFIRI) and veliparib as a second line of therapy work…NCT02890355·Mobile, Alabama and 782 others

CompletedGemcitabine/Capecitabine/ZD6474 in Advanced Solid TumorsZactima will be used in this study to determine the highest dose that can be given safely as well as the side effects of Zactima when in combination with two FDA approved drugs…NCT00551096·Aurora, Colorado

RecruitingAPOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 MutationThis phase II trial investigates how well the addition of olaparib following completion of surgery and chemotherapy works in treating patients with pancreatic cancer that has been…NCT04858334·Anchorage, Alaska and 453 others

CompletedS9700 Combination Chemotherapy in Treating Patients With Stage II or Stage III Pancreatic CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00003018·Mobile, Alabama and 83 others

CompletedBevacizumab, Gemcitabine, and Oxaliplatin in Treating Patients With Metastatic Pancreatic CancerRATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00112528·Mobile, Alabama and 200 others

Active not recruitingNivolumab and Ipilimumab in Treating Patients With Rare TumorsThis phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors.NCT02834013·Birmingham, Alabama and 1006 others

TerminatedStudy of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid TumorsThis study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene…NCT04383210·Birmingham, Alabama and 41 others

RecruitingStudy to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC PatientsTNG462-C102 is a Phase 1/2, open-label, multicenter study designed to determine the safety, tolerability, PK, PD, and preliminary antineoplastic activity of oral TNG462 in…NCT06922591·Scottsdale, Arizona and 17 others

Active not recruitingAbemaciclib in Treating Patients With Advanced, Refractory, and Unresectable Digestive System Neuroendocrine TumorsThis phase II trial studies how well abemaciclib works in treating patients with digestive system neuroendocrine tumors that have spread to other places in the body, do not…NCT03891784·Denver, Colorado and 1 other

TerminatedStudy to Evaluate TNG348 Alone and With a PARP Inhibitor in Patients With BRCA 1/2 Mutant or HRD+ Solid TumorsThe goal of this interventional clinical trial is to learn about TNG348, a ubiquitin specific peptidase 1 (USP1) inhibitor, alone and in combination with olaparib in patients with…NCT06065059·Denver, Colorado and 6 others

CompletedSafety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer SettingTest the safety, immune response and efficacy of GVAX pancreas vaccine (with cyclophosphamide) and CRS-207 compared to chemotherapy or CRS-207 alone in adults with previously…NCT02004262·Scottsdale, Arizona and 20 others

CompletedFluorouracil, Gemcitabine, and Radiation Therapy in Treating Patients With Cancer of the PancreasRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003216·Birmingham, Alabama and 106 others

CompletedS0205 Gemcitabine w/ or w/o Cetuximab as First-Line Therapy in Locally Advanced Pancreas CancerRATIONALE: Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop tumor cells from dividing so they stop growing or die.NCT00075686·Mobile, Alabama and 388 others

RecruitingA Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal AdenocarcinomaThe purpose of this study is to evaluate the efficacy and safety of standard chemotherapy with or without INCB161734 in participants with metastatic pancreatic ductal…NCT07522073·Birmingham, Alabama and 227 others

Active not recruitingTesting the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA MutationsThis phase II trial studies whether adding pembrolizumab to olaparib (standard of care) works better than olaparib alone in treating patients with pancreatic cancer with germline…NCT04548752·Anchorage, Alaska and 532 others

CompletedLEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE)The purpose of this signal seeking study was to determine whether treatment with LEE011 demonstrates sufficient efficacy in CDK4/6 pathway activated solid tumors and/or…NCT02187783·Birmingham, Alabama and 60 others

RecruitingDose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid TumorsThis study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2001 in patients with advanced solid tumors.NCT06239194·Denver, Colorado and 5 others

CompletedNab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (the "Apact" Study)The purpose of this study is to compare whether there is a delay or prevention of recurrence or death in participants with surgically removed pancreatic cancer who then take…NCT01964430·Scottsdale, Arizona and 340 others

CompletedA Study of IMM-6-415 in RAS/RAF Mutant Solid TumorsThis is a FIH, ascending dose study to characterize the safety, tolerability, optimal dose and preliminary anti-tumor activity of IMM-6-415 in participants with advanced or…NCT06208124·Scottsdale, Arizona and 4 others

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Clareo Health | Pancreatic Cancer Clinical Trials in Denver | 129 Studies