Ovarian Cancer Clinical Trials in Pittsburgh

Showing 101-120 of 224 trials

Delayed Initiation of Olaparib Maintenance Therapy in Platinum Sensitive Recurrent Ovarian Cancer

NCT04377087

The purpose of this study is to test if delaying the start of the olaparib until there is a rise in a tumor marker called CA-125 will result in a longer time until the next or different treatment for the patient's cancer. The study will also evaluate how delaying the start of maintenance therapy will affect symptoms; physical functioning; quality of life; and impact on finances.

Ovarian Cancer

Sarah E Taylor3 participantsStarted Jun 2020

Pittsburgh, Pennsylvania, United States

TERMINATEDPhase 1/2< 1 mile

A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

NCT04408599

This research study is studying a new drug, NC410, as a possible treatment for advanced or metastatic solid tumors.

Advanced or Metastatic Solid TumorsOvarian CancerGastric Cancer+1 more

NextCure, Inc.46 participantsStarted Jun 2020

Bethesda, Maryland, United States • Hackensack, New Jersey, United States • New York, New York, United States +2 more locations

TERMINATEDPhase 1< 1 mile

A Study of DeTIL-0255 in Adults With Advanced Malignancies

NCT05107739

This is a first-in-human Phase 1 multicenter, open-label oncology study designed to evaluate the safety and efficacy of NX-DeTIL-0255-201 in patients with advanced malignancies.

Platinum-resistant Ovarian CancerEndometrial CancerCervical Cancer

Nurix Therapeutics, Inc.5 participantsStarted Dec 2021

New Brunswick, New Jersey, United States • Buffalo, New York, United States • Pittsburgh, Pennsylvania, United States +1 more locations

Delayed Initiation of Olaparib Maintenance Therapy in Platinum Sensitive Recurrent Ovarian Cancer

A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

A Study of DeTIL-0255 in Adults With Advanced Malignancies

Ovarian Cancer Trials in Other Cities

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

CB-839 in Combination With Niraparib in Platinum Resistant BRCA -Wild-type Ovarian Cancer Patients

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

A Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid Tumors

SGI-110 in Combination With Carboplatin in Ovarian Cancer

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

A Study Evaluating the Safety, Pharmacokinetics and Efficacy of Ipatasertib Administered in Combination With Rucaparib in Participants With Advanced Breast, Ovarian Cancer, and Prostate Cancer.

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours

Study of ADCT-301 in Patients With Selected Advanced Solid Tumors

Study of CYH33 in Combination With Olaparib an Oral PARP Inhibitor in Patients With Advanced Solid Tumors.

A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR)

Other Conditions in Pittsburgh