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Clinical Trials Ovarian CancerCleveland

Ovarian Cancer Clinical Trials in Cleveland

Find 237 clinical trials for ovarian cancer near Cleveland, Ohio. Connect with research centers in your area.

All Ovarian Cancer trials nationwide All trials in Cleveland

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 121-140 of 237 trials

RecruitingTesting Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial CarcinomaThis phase II trial tests whether the combination of nivolumab and ipilimumab is better than nivolumab alone to shrink tumors in patients with deficient mismatch repair system…NCT05112601·Birmingham, Alabama and 137 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS MutationThis study will assess the safety and efficacy of avutometinib (VS-6766) monotherapy and in combination with defactinib in subjects with recurrent Low-Grade Serous Ovarian Cancer…NCT04625270·Scottsdale, Arizona and 46 others

RecruitingA Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian CancerThis study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (ICT) in subjects with recurrent…NCT06072781·Phoenix, Arizona and 104 others

Active not recruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)This phase II MATCH screening and multi-sub-trial studies how well treatment that is directed by genetic testing works in patients with solid tumors, lymphomas, or multiple…NCT02465060·Birmingham, Alabama and 1409 others

Active not recruitingDurvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer PatientsThis is a Phase III randomised, double-blind, multi-centre study to evaluate the efficacy and safety of durvalumab in combination with standard of care platinum based chemotherapy…NCT03737643·Foothill Ranch, California and 213 others

TerminatedEfficacy and Safety of Farletuzumab (MORAb-003) in Combination With Carboplatin and Taxane in Participants With Platinum-sensitive Ovarian Cancer in First RelapseThis research is being done to find out if Carboplatin and Taxane works better alone or when given with an experimental drug called MORAb-003(farletuzumab) in subjects with first…NCT00849667·Birmingham, Alabama and 374 others

CompletedBioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic MalignanciesThis is a Phase 1, open-label, multicenter, randomized, 2-stage crossover study consisting of 2 phases: Stage I - Pharmacokinetics (Bioequivalence), with an Extension Stage II -…NCT02223052·Scottsdale, Arizona and 9 others

CompletedPaclitaxel Plus Gemcitabine in Treating Patients With Refractory Metastatic Germ Cell TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00003518·Denver, Colorado and 18 others

RecruitingcfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseThis is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer…NCT05366881·Duarte, California and 16 others

CompletedBCX-1777 in Treating Patients With Refractory CancerRATIONALE: BCX-1777 may stop the growth of cancer cells by blocking the enzymes necessary for their growth.NCT00073944·Cleveland, Ohio

RecruitingStudy Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid TumorsHWK-007-101 is a multicenter, open-label, first-in-human (FIH) Phase 1 study evaluating HWK-007, a protein tyrosine kinase 7 (PTK7)-targeted antibody drug conjugate (ADC), in…NCT07444814·Little Rock, Arkansas and 11 others

CompletedSunitinib Malate in Treating Patients With Persistent or Recurrent Clear Cell Ovarian CancerThis phase II trial studies the side effects of sunitinib malate and how well it works in treating patients with ovarian cancer that is persistent or has come back.NCT00979992·Birmingham, Alabama and 96 others

CompletedEGEN-001 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal CancerThis phase II trial studies the side effects and how well EGEN-001 works in treating patients with ovarian epithelial cancer, fallopian tube cancer, or primary peritoneal cancer…NCT01118052·Birmingham, Alabama and 10 others

CompletedBevacizumab and Intravenous or Intraperitoneal Chemotherapy in Treating Patients With Stage II-III Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal CancerThis randomized phase III trial studies bevacizumab and intravenous (given into a vein) chemotherapy to see how well they work compared with bevacizumab and intraperitoneal (given…NCT00951496·Birmingham, Alabama and 502 others

Active not recruitingComparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic AgentsThis phase II trial studies the possible benefits of treatment with different combinations of the drugs durvalumab, olaparib and cediranib vs. the usual treatment in patients with…NCT04739800·Anchorage, Alaska and 390 others

CompletedPhase I Study of Intravenous Triapine (IND # 68338) in Combination With Pelvic Radiation Therapy With or Without Weekly Intravenous Cisplatin Chemotherapy for Locally Advanced Cervical, Vaginal, or Pelvic Gynecologic MalignanciesDrugs used in chemotherapy, such as 3-AP and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.NCT00335998·Cleveland, Ohio

Active not recruitingA Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based ChemotherapyThis is a Phase 3, randomized, multinational, double-blind, dual placebo-controlled, 4-arm study evaluating rucaparib and nivolumab as maintenance treatment following response to…NCT03522246·Phoenix, Arizona and 237 others

TerminatedAn Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian CancerThe study is being conducted to find out if paclitaxel works better when given together with an experimental drug called MORAb-003 (farletuzumab) or alone in patients with…NCT00738699·Mobile, Alabama and 60 others

TerminatedA Safety Study of SGN-CD47M in Patients With Solid TumorsThis trial will study SGN-CD47M to find out whether it is an effective treatment for different types of solid tumors and what side effects (unwanted effects) may occur.NCT03957096·Cleveland, Ohio and 4 others

Active not recruitingPaclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube CancerThis phase III clinical trial studies two different dose schedules of paclitaxel to see how well they work in combination with carboplatin with or without bevacizumab in treating…NCT01167712·Birmingham, Alabama and 563 others

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