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Clareo Health | Melanoma Clinical Trials in Philadelphia | 224 Studies

Clinical Trials MelanomaPhiladelphia

Melanoma Clinical Trials in Philadelphia

Find 224 clinical trials for melanoma near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 201-220 of 224 trials

CompletedEfficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in MelanomaThe objective of this study is to evaluate the efficacy and safety of treatment with talimogene laherparepvec compared to subcutaneously administered GM-CSF in patients with…NCT00769704·Tucson, Arizona and 82 others

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Data from ClinicalTrials.govTerms

RecruitingComparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage MelanomaThis phase III trial compares the effect of wide local excision (WLE) alone to usual care with WLE plus sentinel lymph node (SLN) biopsy for the treatment of older adults with…NCT07068074·Birmingham, Alabama and 180 others

RecruitingACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid TumorsThe study's purpose is to establish the safety and tolerability of IMA203/IMA203CD8 products with or without combination with nivolumab in patients with solid tumors that express…NCT03686124·Stanford, California and 20 others

TerminatedA Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV MelanomaThe purpose of this study is to assess nivolumab plus relatlimab fixed-dose combination (FDC) versus nivolumab alone in participants with completely resected stage III-IV melanoma.NCT05002569·Birmingham, Alabama and 183 others

CompletedPhase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck CancerTo determine a safe and effective doses of two biologic drugs, erlotinib and bevacizumab when used with chemotherapy and radiation therapy in advanced head and neck cancerNCT00405405·Philadelphia, Pennsylvania

CompletedDendritic Cell Vaccination in Patients With Advanced MelanomaThe purpose of this study is to investigate a method of using dendritic cells (a kind of white blood cell) as a vaccine to stimulate your own immune system to react to your…NCT03092453·Philadelphia, Pennsylvania

CompletedA Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01949 when given in combination with immune therapies in participants with advanced or…NCT03241173·Birmingham, Alabama and 14 others

CompletedA Study of Vemurafenib Adjuvant Therapy in Participants With Surgically Resected Cutaneous BRAF-Mutant MelanomaThis multicenter, randomized, double-blind, placebo-controlled study will evaluate the efficacy and safety of vemurafenib in participants with completely resected, cutaneous BRAF…NCT01667419·Birmingham, Alabama and 206 others

Active not recruitingMelmarT Melanoma Margins Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous MelanomaPatients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin.NCT02385214·Philadelphia, Pennsylvania and 19 others

CompletedTemsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid TumorsThis phase I trial is studying the side effects and best dose of temsirolimus when given together with bryostatin 1 in treating patients with unresectable or metastatic solid…NCT00112476·Philadelphia, Pennsylvania

Active not recruitingStudy Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With PembrolizumabThis Phase 1/2, first-in-human, open-label, multicenter study follows a 3+3 ascending dose escalation design to determine the MTD/RP2D and to characterize the safety…NCT04130516·Los Angeles, California and 9 others

CompletedNivolumab in Treating Patients With Stage IIB-IIC Melanoma That Can Be Removed by SurgeryThis phase II trial studies how well nivolumab works in treating patients with stage IIB-IIC melanoma that can be removed by surgery.NCT03405155·New Brunswick, New Jersey and 3 others

CompletedModifying Young Adult Skin Cancer Risk and Protective BehaviorsSkin cancer is the most common cancer and can be deadly, debilitating, damaging, and disfiguring, yet is highly preventable.NCT03313492·New Brunswick, New Jersey and 1 other

RecruitingProject: Every Child for Younger Patients With CancerThis study gathers health information for the Project: Every Child for younger patients with cancer.NCT02402244·Birmingham, Alabama and 278 others

CompletedTrial of Autologous, Hapten-Modified Vaccine in Patients With Stage III or IV MelanomaThe purpose of this study is to determine whether a vaccine composed of patients' own melanoma cells treated with the chemical, dinitrophenyl (DNP)(called a hapten), is safe and…NCT00257465·Tucson, Arizona and 6 others

TerminatedA Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid TumorsThis study will evaluate the efficacy and safety of alectinib in participants with Anaplastic Lymphoma Kinase (ALK)-positive locally advanced or metastatic solid tumors other than…NCT04644315·Culver City, California and 28 others

CompletedStudy of MLN2480 in Participants With Relapsed or Refractory Solid Tumors Followed by a Dose Expansion in Participants With Metastatic MelanomaThis is a phase 1, multicenter, nonrandomized, open-label, dose escalation study. The study will be conducted in 2 stages, Dose Escalation and Dose Expansion.NCT01425008·San Francisco, California and 15 others

TerminatedNY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)This is a first-in-human trial proposed to test HLA-A\*0201 restricted NY-ESO-1 redirected T cells with edited endogenous T cell receptor and PD-1.NCT03399448·Philadelphia, Pennsylvania

CompletedA Study of RO5185426 in Patients With Metastatic MelanomaThis is an open-label, non-comparative, multicenter, expanded access study of RO5185426 in patients who have received prior systemic therapy for metastatic melanoma and who have…NCT01248936·Tucson, Arizona and 27 others

CompletedVaccine Therapy in Treating Patients With Stage IV MelanomaRandomized phase I trial to study the effectiveness of vaccine therapy in treating patients who have stage IV melanoma.NCT00003665·Philadelphia, Pennsylvania

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