Lupus Clinical Trials

Showing 101-120 of 3,134 trials

Investigation of the Effect of Thoracic Manipulation and Classical Massage on Pain, Flexibility and Sleep Quality

NCT07518732

Investigation Of The Effects Of Thoracic Manipulation And Classical Massage On Pain Flexibility And Sleep Quality In Patients With Mechanical Back Pain

MECHANICAL BACK PAINSleep Quality

Ayşe BAŞAYAN60 participantsStarted Apr 2026

Istanbul, Turkey (Türkiye)

RECRUITING

Impact of Transcatheter Aortic Valve Implantation and Mitral Valve Repair on Sleep-Disordered Breathing

NCT07520656

This prospective observational study aims to investigate the impact of transcatheter aortic valve implantation (TAVI) and transcatheter mitral valve edge-to-edge repair (M-TEER) on sleep-disordered breathing (SDB) in patients with significant valvular heart disease. Patients undergoing TAVI or M-TEER will be evaluated with full polysomnography prior to the intervention and at 6 months follow-up. Changes in sleep parameters, including apnea-hypopnea index (AHI), central and obstructive apnea indices, oxygen desaturation, and sleep architecture, will be assessed. In addition, the study will explore the association between changes in SDB and echocardiographic as well as arrhythmic parameters. The findings are expected to improve the understanding of the interaction between valvular heart disease and SDB and to identify potential benefits of transcatheter interventions on sleep-related outcomes.

Sleep-disordered Breathing (SDB)Aortic Valve StenosisMitral Valve Regurgitation

Aristides Plaitis150 participantsStarted Jul 2025

Athens, Attica, Greece

RECRUITINGPhase 1/2

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

NCT07089121

Safety, tolerability and efficacy of Descarte-08 in children, adolescents and young adults with childhood-onset systemic lupus erythematosus, ANCA-associated vasculitis, juvenile myasthenia gravis, and juvenile dermatomyositis

Childhood-onset Systemic Lupus ErythematousANCA-Associated Vasculitis (AAV)Juvenile Myasthenia Gravis+1 more

Cartesian Therapeutics50 participantsStarted Jan 2026

Washington D.C., District of Columbia, United States • St Louis, Missouri, United States

Investigation of the Effect of Thoracic Manipulation and Classical Massage on Pain, Flexibility and Sleep Quality

Impact of Transcatheter Aortic Valve Implantation and Mitral Valve Repair on Sleep-Disordered Breathing

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

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Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury

Sleep Apnea Diagnosis Using a Novel Pacemaker Algorithm and Link With Aldosterone Plasma Level in Patients Presenting With Diastolic Dysfunction

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A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus

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