Lupus Clinical Trials

Showing 441-460 of 2,686 trials

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP)

NCT06752876

This is a Phase 1 study to evaluate the safety and efficacy of a single infusion of CB-010 in patients with refractory Systemic Lupus Erythematosus (SLE) with cohorts for lupus nephritis (LN) and extrarenal lupus (ERL).

Systemic Lupus ErythematosusLupusLupus Erythematosus+1 more

Caribou Biosciences, Inc.Started Dec 2027

Active Not RecruitingPhase 1

A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus

NCT05411016

Part 1 : To evaluate the safety and tolerability of a single intravenous (IV) or subcutaneous (SC) dose of KK4277 in healthy Japanese or non-Asian adult males. Part 2 : To evaluate the safety and tolerability of repeated IV or SC administration of KK4277 in patients with Systemic lupus erythematosus (SLE) or Cutaneous lupus erythematosus (CLE).

Healthy VolunteersSystemic Lupus Erythematosus (SLE)Cutaneous Lupus Erythematosus (CLE)

Kyowa Kirin Co., Ltd.157 participantsStarted Aug 2022

Kutsukake, Aichi-ken, Japan • Minami, Aichi-ken, Japan • Urayasu, Chiba, Japan +20 more locations

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP)

A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus

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