Lung Cancer Clinical Trials

Showing 1761-1780 of 4,288 trials

Efficacy and Safety of Intraventricule Pemetrexed Disodium Administered Via Ommaya Reservoir

NCT06399926

This is a open-label, multi-center prospective observation study for the efficacy and safety of intraventricle pemetrexed disodium via ommaya reservoir in the treatment of leptomeningeal metastasis with lung cancer who have failed at least one targeted therapy. In detail: At least the treatment failure was after third-generation EGFR-TKIs in EGFR-mutated lung cancer; or at least the treatment failure was after second-generation ALK-TKIs in ALK-mutated lung cancer; or at least the treatment failure was after one-line of targeted-TKIs in ROS1-mutated non-squamous non-small lung cancer.

Leptomeningeal MetastasisLung Cancer

Xiangya Hospital of Central South University64 participantsStarted Oct 2023

Changsha, Hunan, China

COMPLETED

Tailoring Shared Decision Making for Lung Cancer Screening in Persons Living With HIV

NCT04682301

This study tailors a shared decision making intervention for lung cancer screening in persons living with human immunodeficiency virus (HIV). Information collected in this study may help doctors better understand how to perform lung cancer screening in persons living with HIV, so as to enhance shared decision making in persons living with HIV.

Lung Carcinoma

Fred Hutchinson Cancer Center102 participantsStarted Feb 2021

Seattle, Washington, United States

COMPLETEDPhase 2

Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.

NCT01928576

Response Rate

Non-Small Cell Lung CancerEpigenetic Therapy

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins143 participantsStarted Nov 2013

Los Angeles, California, United States • Washington D.C., District of Columbia, United States • Baltimore, Maryland, United States +2 more locations

Efficacy and Safety of Intraventricule Pemetrexed Disodium Administered Via Ommaya Reservoir

Tailoring Shared Decision Making for Lung Cancer Screening in Persons Living With HIV

Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.

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D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure

Effect of Low-dose Radiotherapy on Tumor Immune Microenvironment in Oligometastases of NSCLC After Immunotherapy

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SNC115 Injections in Patients With Recurrent/Refractory Small Cell Lung Cancer and Lung Large Cell Neuroendocrine Carcinoma

The Feasibility of Dynamic Liquid Biopsy Monitoring During Neoadjuvant Treatment for EGFR-mutated NSCLC

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Patient Reported Outcomes Study Using Electronic Monitoring System for Advanced or Metastatic Solid Cancer

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An Observational Study to Evaluate Neoadjuvant Nivolumab (OPDIVO®) in Combination With Platinum-Based Chemotherapy in Non-Metastatic Non-Small Cell Lung Cancer Participants in Germany

A Nested Case-Control Study of Lung Cancer and Diesel Exhaust Among Non-Metal Miners