Lung Cancer Clinical Trials

Showing 1681-1700 of 2,032 trials

Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

NCT01155258

RATIONALE: Temsirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as vinorelbine ditartrate, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving temsirolimus together with vinorelbine ditartrate may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of giving temsirolimus and vinorelbine ditartrate together in treating patients with unresectable or metastatic solid tumors.

Extensive Stage Small Cell Lung CancerHereditary ParagangliomaMale Breast Cancer+45 more

University of Southern California19 participantsStarted Jun 2010

Los Angeles, California, United States

COMPLETEDPhase 1

SORAVE - Sorafenib and Everolimus in Solid Tumors

NCT00933777

Dose finding part: A phase I clinical trial to evaluate the safety of combined sorafenib and everolimus treatment in patients with relapsed solid tumors (finished). Extension part:Treatment of non-small cell lung cancer (NSCLC) with KRAS mutation after ≥ 1st relapse (recruiting)

Unspecified Adult Solid Tumor, Protocol SpecificNon-Small Cell Lung Cancer

University of Cologne36 participantsStarted Jul 2009

Cologne, Germany

Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

SORAVE - Sorafenib and Everolimus in Solid Tumors

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