Lung Cancer Clinical Trials

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Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC

NCT06123754

This is a randomized, controlled, double-blind, multicenter Phase 3 clinical study to assess the efficacy and safety of envafolimab plus platinum-based doublet chemotherapy versus placebo plus platinum-based doublet chemotherapy as neoadjuvant/adjuvant therapy in subjects with resectable stage IIIA and IIIB (N2) NSCLC. Primary study endpoints are MPR rate assessed by BIPR and EFS assessed by BIRC.

Non-small Cell Lung Cancer

3D Medicines (Sichuan) Co., Ltd.390 participantsStarted Nov 2023

Tianjin, Tianjin Municipality, China

COMPLETEDPhase 1

TGRX-326 Pharmacokinetic Food Effect Bioavailability Study

NCT06304805

A study evaluating the effects of food intake on the pharmacokinetic (PK) profiles of TGRX-326 and the effect of different drug specifications on human bioavailability for TGRX-326, a drug indicated for non-small cell lung cancer treatment

Non Small Cell Lung Cancer

Shenzhen TargetRx Co., Ltd.24 participantsStarted Dec 2023

Bengbu, Anhui, China

Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC

TGRX-326 Pharmacokinetic Food Effect Bioavailability Study

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Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer

A Phase 1/2 Study to Evaluate the Safety, Tolerability and PK of JIN-A02 in Patients With EGFR Mutant Advanced NSCLC

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Trial of Trametinib and Ponatinib in Patients With KRAS Mutant Advanced Non-Small Cell Lung Cancer

A Study of Mobocertinib in Japanese Adults With Non-Small Cell Lung Cancer

Continued Access to RXDX-105

Automated Device for Asthma Monitoring and Management in Monitoring Adults With Lung Cancer Undergoing Radiation Therapy

Neoadjuvant Sacituzumab Govitecan Plus Pembrolizumab in Resectable Non-Small Cell Lung Cancer

Pre-habilitation in Lung Surgery Candidates

Plasma Proteomic Biomarkers for Early Diagnosis of Lung Cancer

Clinical Study of Combined EphA2-targeted CAR-DC and CAR-T Cell Therapy for Non-small Cell Lung Cancer

High-Dose Firmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed in the Treatment of EGFR-Mutated Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Couple-Based Meditation for Metastatic Lung Cancer Patients and Their Partners

Survivorship Study of Cancer Patients Who Received Cranial Radiation Therapy