Lung Cancer Clinical Trials

Showing 781-800 of 2,032 trials

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

NCT06497530

This is a single-arm, open-lable exploratory study of Lurbinectedin in combination with Serplulimab as maintenance therapy in participants with extensive-stage small-cell lung cancer (ES-SCLC) after first-line induction therapy with carboplatin, etoposide, and Serplulimab. The study consists of 2 phases: an induction phase and a maintenance phase. Participants need to have an ongoing response or stable disease per the Response Evaluation Criteria in Solid Tumor (RECIST) v1.1 criteria after completion of 4 cycles of carboplatin, etoposide, and Serplulimab induction treatment in order to be considered for eligibility screening for the maintenance phase. Eligible participants will receive lurbinectedin plus Serplulimab in the maintenance phase.

Extensive-Stage Small Cell Lung Cancer

Guangzhou Institute of Respiratory Disease30 participantsStarted Aug 2024

RECRUITINGNA

The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis

NCT06244264

The goal of this single-center prospective randomized controlled trial is to test and compare the safety and effectiveness of autologous blood transfusion in spinal surgery for lung cancer spinal metastases. The main questions it aims to answer are: * Does autologous blood transfusion increase the incidence of new metastases? * Does autologous blood transfusion affect postoperative hemoglobin levels and the number of circulating tumor cells in the blood? * Can autologous blood transfusion reduce the rate of allogeneic transfusion during and after surgery for spinal metastases?

Spinal MetastasesBlood Transfusion ComplicationLung Cancer+2 more

Guangdong Provincial People's Hospital118 participantsStarted Mar 2024

Guangzhou, Guangdong, China

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis

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