Leukemia Clinical Trials

Showing 1501-1520 of 10,987 trials

Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia

NCT05417165

This phase II trial compares the effect of initial vaccination (PCV20 followed by PSV23) with yearly vaccinations of PSV23 to the standard 5 year vaccination in patients with chronic lymphocytic leukemia. At present chronic lymphocytic leukemia patients are poorly protected by anti-pneumococcal vaccination. Current vaccination schedule for chronic lymphocytic leukemia patients is based on general recommendations in immunocompromised patients (initial vaccination with PCV13 followed by one dose of PSV23 after an interval of two months, followed by revaccination at 5 years). Giving patients frequent immunization as compared to 5 year immunization may result in higher protective titers in patients.

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma

Seema Bhat80 participantsStarted Sep 2023

Columbus, Ohio, United States

RECRUITINGPhase 2

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

NCT00501826

This phase II trial studies the side effects and how well combination chemotherapy and nelarabine work in treating patients with T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma. Drugs used in chemotherapy, such as cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, cytarabine, mercaptopurine, prednisone, pegaspargase, nelarabine, and venetoclax work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

T Acute Lymphoblastic LeukemiaT Lymphoblastic Lymphoma

M.D. Anderson Cancer Center160 participantsStarted Jul 2007

Houston, Texas, United States

Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Related Searches

A Long-Term Study of TAU-284 in Pediatric Patients With Perennial Allergic Rhinitis

An Intervention to Help Patients and Caregivers Manage Stress and Improve Communication Skills When Talking About Cancer

Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS)

A Confirmatory Study of TAU-284 in Pediatric Patients With Perennial Allergic Rhinitis

Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

ACY-1215 in Combination With BCR Pathway Inhibitors in Relapsed CLL

PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia

Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma

Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers

First-in-Human, Phase I, Open-label, Multicenter, Dose Escalation Clinical Study

REtreatment With VEnetoclax and Acalabrutinib After Venetoclax Limited Duration (REVEAL)

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

JY231 (JY231) Injection for the Treatment of B-cell Acute Lymphoblastic Leukemia (B-ALL)

Pre-DLI or Pro-DLI in Relapsed/Refractory Myeloid Neoplasms After HSCT

An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study