Leukemia Clinical Trials

Showing 6641-6660 of 8,366 trials

Investigate the Safety and Tolerability of AZD6244 Monotherapy or + Docetaxel in Japanese Patients With Advanced Solid Malignancies or Non-Small Cell Lung Cancer

NCT01605916

The objective of this study will be to investigate the safety and tolerability of AZD6244 given monotherapy or in combination with docetaxel as 2nd line therapy in Japanese patients with Advanced Solid Malignancies or Locally Advanced or Metastatic Non-Small Cell Lung Cancer. In addition, the pharmacokinetic profile of AZD6244 will be investigated. Following the combination regimen dose escalation phase (Part A) of the study additional patients may be enrolled to a dose expansion phase (Part B) to refine further the safety, tolerability, pharmacokinetics and biological activity of the combination in this patient population.

Neoplasms,Metastatic Cancer,Non-Small Cell Lung Cancer+1 more

AstraZeneca33 participantsStarted Jun 2012

Fukuoka, Japan • Kashiwa-shi, Japan • Nagoya, Japan

UNKNOWNPhase 3

18F-FDG Metabolism Imaging Monitoring Non-small Cell Lung Cancer Curative Effect of Chemotherapy Multicenter Clinical Study

NCT02938546

The subject is going to use 18F-FDG PET/CT to assess different genetic NSCLC metabolism after cisplatin chemotherapy and targeted therapy, define the assessment criteria for the role of 18F-FDG PET/CT in NSCLC treatment respone and at last build multi-centre clinical trial platform of molecular classification and molecular imaging for cancer chemotherapy assessment.

Non-small-cell Lung Cancer

Shanghai Chest Hospital200 participantsStarted Nov 2016

UNKNOWNPhase 2

Erlotinib in Post Radical Operation NSCLC Patients With EGFR Mutation

NCT01683175

This study is to compare 2-year Disease Free Survival Rate (DFSR) in post radical operation IIIA Non-Small Cell Lung Cancer (NSCLC) patients with Epidermal Growth Factor Receptor (EGFR) 19 or 21 exon mutation treated Erlotinib vs NP chemotherapy as adjuvant therapy.

Non-small Cell Lung Cancer Stage III

Tianjin Medical University Cancer Institute and Hospital94 participantsStarted Aug 2012

Tianjin, Tianjin Municipality, China • Beijing, China • Beijing, China +12 more locations

Investigate the Safety and Tolerability of AZD6244 Monotherapy or + Docetaxel in Japanese Patients With Advanced Solid Malignancies or Non-Small Cell Lung Cancer

18F-FDG Metabolism Imaging Monitoring Non-small Cell Lung Cancer Curative Effect of Chemotherapy Multicenter Clinical Study

Erlotinib in Post Radical Operation NSCLC Patients With EGFR Mutation

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