Leukemia Clinical Trials

Showing 5641-5660 of 8,366 trials

Health Related Quality of Life of Patients With Abdominal Wall Defects

NCT03960320

Examination of the health-related quality of life of patients operated on due to congenital defects of the abdominal wall after birth with the questionnaires KINDL, SDQ and SF-36.

Quality of LifeAbdominal Wall DefectGastroschisis+1 more

Universität des Saarlandes65 participantsStarted May 2014

TERMINATEDPhase 1/2

Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway

NCT01601184

The purpose of this study is to evaluate the safety of vismodegib in combination with temozolomide (primary objective - phase I) and to estimate the efficacy of vismodegib in combination with temozolomide in adult patients with recurrent, progressive, or refractory medulloblastomas to standard therapy measured by the 6-month progression-free rate (phase II). This study is an open-label Phase I/II, international, randomized. 38 patients will be included in the study.

Histologically Confirmed MedulloblastomaActivation of the Sonic Hedgehog (SHH) Pathway

Centre Leon Berard24 participantsStarted Jun 2012

Marseille, Bouches Du Rhône, France • Toulouse, Haute-Garonne, France • Saint-Herblain, Loire Atlantique, France +12 more locations

Health Related Quality of Life of Patients With Abdominal Wall Defects

Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway

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