Leukemia Clinical Trials

Showing 541-560 of 8,366 trials

WiseApp for Spanish Speakers Living With HIV

NCT05398185

This study aims to conduct a 12-month randomized controlled trial to adapt the mobile app, WiseApp, and a smart pill dispenser for Spanish-speaking people living with HIV (PLWH) in the New York City (NYC) area and La Romana, Dominican Republic (DR). The study will assess the efficacy and sustainability of WiseApp as well as identify barriers with its widespread use among Spanish speakers. With disproportionately high rates of HIV in the New York City area and the Dominican Republic, this project seeks to identify distinct contextual factors related to Spanish speaking people living with HIV and increase the likelihood of engagement with technology and improvements in clinical outcomes.

HIV InfectionsAcquired Immune Deficiency SyndromeSexually Transmitted Diseases, Viral

Columbia University248 participantsStarted Mar 2023

New York, New York, United States • La Romana, Dominican Republic

RECRUITINGNA

Promoting Immunotherapy Efficacy With Low-Dose Liver RT

NCT07225036

The purpose of this study is to see if adding Low-Dose Liver Radiation (LD-LRT) improves progression free survival (PFS). This study is for patients with either melanoma or non-small cell lung cancer (NSCLC), with liver metastases, and receiving immunotherapy.

Low-Dose Liver Radiation (LD-LRT)Non Small Cell Lung CancerMelanoma+1 more

Jordan Kharofa21 participantsStarted Dec 2025

Cincinnati, Ohio, United States

TERMINATEDPhase 1/2

A Phase I/II Study of ASTX660 in Patients With Relapsed or Refractory T-cell Lymphoma

NCT04362007

Phase 1 (dose-escalation part): Investigate the tolerability and safety of ASTX660 in patients with r/r PTCL and r/r CTCL and determine the recommended dose (RD) for the Phase 2. Phase 1 (ATLL expansion part): Evaluate the safety of ASTX660 at RD in patients with r/r ATLL. Phase 2 : Evaluate the efficacy of ASTX660 at RD in patients with r/r PTCL.

Relapsed or Refractory Peripheral T-cell Lymphoma(PTCL),Cutaneous T-cell Lymphoma(CTCL),Adult T-cell Leukemia/Lymphoma(ATLL)

Otsuka Pharmaceutical Co., Ltd.8 participantsStarted Jul 2020

Yamagata, Japan

WiseApp for Spanish Speakers Living With HIV

Promoting Immunotherapy Efficacy With Low-Dose Liver RT

A Phase I/II Study of ASTX660 in Patients With Relapsed or Refractory T-cell Lymphoma

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Application of Device-based Training to Improve Postural Control in Older Adults With CCI

Comparison of Smartphone and Community-Based Delivery of the Otago Exercise Program for Fall Risk in Older Adults

Study of Efficacy and Safety of Pembrolizumab Plus Platinum-based Doublet Chemotherapy With or Without Canakinumab in Previously Untreated Locally Advanced or Metastatic Non-squamous and Squamous NSCLC Subjects

Talazoparib for Cohesin-Mutated AML and MDS With Excess Blasts

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer

A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors.

PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer

A Study of TAK-788 in Adults With Non-Small Cell Lung Cancer

Dual-Task vs. Multicomponent Exercise in Institutionalized Seniors

Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)

Cryopreserved MMUD BM With PTCy for Hematologic Malignancies

The Low FODMAP Diet in Individuals With Small Intestinal Bacterial Overgrowth (SIBO)

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell Transplantation

Acalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Evaluation of Small Vessel Disease by 3D-rotational Angiography