Leukemia Clinical Trials

Showing 2221-2240 of 5,235 trials

Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery

NCT06050161

This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.

Pelvic Organ ProlapseAbnormal Uterine BleedingMesh Augmentation+4 more

Kern Medical Center50 participantsStarted Sep 2023

COMPLETEDPhase 1

Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

NCT02122081

This pilot clinical trial aims to assess feasibility and tolerability of using an LINAC based "organ-sparing marrow-targeted irradiation" to condition patients with high-risk hematological malignancies who are otherwise ineligible to undergo myeloablative Total body irradiation (TBI)-based conditioning prior to allogeneic stem cell transplant. The target patient populations are those with ALL, AML, MDS who are either elderly (\>50 years of age) but healthy, or younger patients with worse medical comorbidities (HCT-Specific Comorbidity Index Score (HCT-CI) \> 4). The goal is to have the patients benefit from potentially more efficacious myeloablative radiation based conditioning approach without the side effects associated with TBI.

Adult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities+12 more

Sumithira Vasu33 participantsStarted Jul 2015

Columbus, Ohio, United States

Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery

Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

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Natural Killer(NK) Cell Therapy Targeting CLL1 in Acute Myeloid Leukemia