Leukemia Clinical Trials in Pittsburgh

Showing 701-720 of 1,534 trials

Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.

NCT01928576

Response Rate

Non-Small Cell Lung CancerEpigenetic Therapy

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins143 participantsStarted Nov 2013

Los Angeles, California, United States • Washington D.C., District of Columbia, United States • Baltimore, Maryland, United States +2 more locations

TERMINATEDPhase 1/2< 1 mile

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

NCT05538624

This is an open-label, First-in-Human, Phase 1/2, multicenter study to evaluate the safety and efficacy of a single dose of AVB-001. AVB-001 is an encapsulated cell product engineered to produce native human interleukin-2 (hIL-2). It is delivered intraperitoneally (IP) to patients with high grade serous adenocarcinoma of the ovary, primary peritoneum, or fallopian tube.

Neoplasm, OvarianFallopian Tube CancerPrimary Peritoneal Cavity Cancer+5 more

Avenge Bio, Inc14 participantsStarted Dec 2022

Bethesda, Maryland, United States • Boston, Massachusetts, United States • Pittsburgh, Pennsylvania, United States +2 more locations

COMPLETEDPhase 3< 1 mile

Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia

NCT00381680

This randomized phase III trial is studying low-dose vincristine to see how well it works compared with high-dose vincristine when given together with different combination chemotherapy regimens in treating young patients with intermediate-risk relapsed B-cell acute lymphoblastic leukemia. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving the drugs in different ways and different doses may kill more cancer cells..

B-cell Childhood Acute Lymphoblastic LeukemiaL1 Childhood Acute Lymphoblastic LeukemiaL2 Childhood Acute Lymphoblastic Leukemia+1 more

Children's Oncology Group275 participantsStarted Mar 2007

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Phoenix, Arizona, United States +170 more locations

Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia

Leukemia Trials in Other Cities

A Study to Compare the Efficacy and Safety of Lisocabtagene Maraleucel vs Investigator's Choice Options in Adult Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, Whose Disease Has Failed Treatment With Both BTKi and BCL2i Therapies

A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML)

An Exploratory Study of the Effects of Nivolumab Combined With Ipilimumab in Patients With Treatment-Naive Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC)

Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)

Ancora-SB Overtube Complete Positioning and Optical Visualization During Endoscopic Procedures

Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation

A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

Pilot Study of Nivolumab in Pediatric Patients With Hypermutant Cancers

Blinatumomab in Adults With Relapsed/Refractory Philadelphia Positive B-precursor Acute Lymphoblastic Leukemia

A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving

Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers Study

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL)

Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies

Other Conditions in Pittsburgh