Leukemia Clinical Trials in Maryland

Showing 901-920 of 1,903 trials

Neuroimmune Dysfunction in Alcohol Use Disorder

NCT04210713

The objective of this proposal is to advance medication development for alcohol use disorder by examining the efficacy and mechanisms of action of minocycline, a neuroimmune modulator, as a potential treatment. This study has important clinical implications, as the available treatments for alcohol use disorder are only modestly effective and testing novel medications is a high research priority.

Alcohol DrinkingAlcohol-Related DisordersDisease+13 more

University of Maryland, Baltimore142 participantsStarted Feb 2020

Catonsville, Maryland, United States

TERMINATEDPhase 117 miles

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

NCT04244552

ATRC-101-A01 is a Phase 1b, open-label dose escalation and expansion trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally occurring human antibody. The safety, tolerability, PK, and biological activity of ATRC-101 will be characterized when administered every two weeks (Q2W) or every 3 weeks (Q3W) as a monotherapy or in combination with other anticancer agents.

Breast CancerColorectal CancerOvarian Cancer+13 more

Atreca, Inc.87 participantsStarted Feb 2020

Phoenix, Arizona, United States • Tucson, Arizona, United States • Duarte, California, United States +16 more locations

Neuroimmune Dysfunction in Alcohol Use Disorder

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Leukemia Trials in Other Cities

BIO 300 Non-Small Cell Lung Cancer Study

CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory CLL

A Study for Oral SY-2101 for Participants With Acute Promyelocytic Leukemia

PET Imaging With [18F]F-AraG in Advanced Non-small Cell Lung Cancer (NSCLC)

Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer

CD40 Agonistic Antibody APX005M (Sotigalimab) in Combination With Nivolumab

A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

A Study of PRT2527 in Participants With Advanced Solid Tumors

Prospective Clinicogenomic Program

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

Lorlatinib in Combination With Chemotherapy in Participants With Metastatic Anaplastic Lymphoma Kinase Positive (ALK+) Non-small Cell Lung Cancer (NSCLC) Who Progressed on Single-agent Lorlatinib

Antigen-specific T Cell Therapy for AML or MDS Patients With Relapsed Disease After Allo-HCT

A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

Study Investigating NTLA-5001 in Subjects With Acute Myeloid Leukemia

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy

Survival Prolongation by Rationale Innovative Genomics

International Lung Screen Trial (ILST)

Other Conditions in Maryland