Leukemia Clinical Trials in Arizona

Showing 681-700 of 1,431 trials

A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

NCT03238027

A Phase 1 dose escalation study to determine if axatilimab as monotherapy and axatilimab in combination with a fixed dose of durvalumab will be sufficiently safe and well-tolerated at biologically active doses to warrant further investigation in patients with solid tumors.

Solid TumorMetastatic TumorLocally Advanced Malignant Neoplasm+1 more

Syndax Pharmaceuticals45 participantsStarted Sep 2017

Scottsdale, Arizona, United States • Baltimore, Maryland, United States • Portland, Oregon, United States +2 more locations

COMPLETEDPhase 131 miles

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

NCT03490669

This is a 2-part study to evaluate the safety and antitumor activity of MSC-1. MSC-1 is a first-in-class, humanized monoclonal antibody (IgG1) which binds to the immunosuppressive human cytokine Leukemia Inhibitory Factor (LIF), and is intended to treat adult patients with Advanced Solid Tumors. In part 1, multiple dose levels of MSC-1 in patients with advanced solid tumors will be studied to determine the recommended dose for further evaluation of safety and efficacy in Part 2.

Advanced Solid TumorsPancreatic CancerNon Small Cell Lung Cancer+1 more

AstraZeneca41 participantsStarted May 2018

Scottsdale, Arizona, United States • Grand Rapids, Michigan, United States • Middletown, New Jersey, United States +4 more locations

TERMINATEDPhase 235 miles

A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF)

NCT03472560

This is a Phase 2 study to evaluate the safety and efficacy of avelumab in combination with axitinib in patients with advanced or metastatic non-small cell lung cancer (NSCLC) who have received at least one prior platinum containing therapy, and in treatment naïve patients with advanced or metastatic urothelial cancer, who are ineligible for cisplatin containing chemotherapy for their advanced disease.

Non-Small Cell Lung CancerUrothelial Cancer

Pfizer61 participantsStarted May 2018

Glendale, Arizona, United States • Goodyear, Arizona, United States • Phoenix, Arizona, United States +36 more locations

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A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF)

Leukemia Trials in Other Cities

Oral Penicillin Challenge and Allergy De-labeling in Children

Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients

Safety Surveillance Cohort Study of Vaccinia Vaccine (ACAM2000®)

House Dust Mite Allergy Trial In Children

A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

Blinatumomab in Adults With Relapsed/Refractory Philadelphia Positive B-precursor Acute Lymphoblastic Leukemia

Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS

Study of ADXS-503 With or Without Pembro in Subjects With Metastatic Non-Small Cell Lung Cancer

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL

Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.

Ancora-SB Overtube Complete Positioning and Optical Visualization During Endoscopic Procedures

Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies

Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation

A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.

Study of ADCT-301 in Patients With Selected Advanced Solid Tumors

Other Conditions in Arizona