Hypertension Clinical Trials

Showing 2041-2060 of 3,518 trials

Virtual Hepatic Venous Pressure Gradient (vHVPG) With CT Angiography (CHESS1601)

NCT02842697

This is a prospective, multi-center trial conducted at 1 Guangzhou and 2 Beijing centers designed to determine the diagnostic performance of virtual hepatic venous pressure gradient (vHVPG) (investigational technology) by anatomic computed tomographic angiography (CTA) for non-invasive assessment of the clinically significant portal hypertension (CSPH) in patients with compensated cirrhosis. Direct hepatic venous pressure gradient (HVPG) measurement by means of catheterization of a hepatic vein with a balloon catheter is the gold-standard method to assess the presence of CSPH, which is defined as HVPG≥10 mmHg.

Hypertension, Portal

Nanfang Hospital, Southern Medical University102 participantsStarted Aug 2016

Beijing, Beijing Municipality, China • Beijing, Beijing Municipality, China • Guangzhou, Guangdong, China

COMPLETEDNA

A Novel Approach for Transjugular Intrahepatic Portocaval Shunt Creation Using Real-time Three Dimensional Roadmap

NCT03031366

TIPS creation has been widely used to treat the complications associated with portal hypertension. In association with increased operator experience and the ongoing development of imaging modalities, the rate of major complications associated with TIPS has decreased significantly in the past decades. However, the passage of a curved needle from the hepatic vein into the portal vein still remains a challenging and time-consuming part of the procedure and is associated with puncture-related complications that are potentially fatal.Three-dimensional roadmap guidance has been widely applied in various interventions. The aim of the present study is to prospectively assess the feasibility and efficacy of real-time 3D roadmap guidance during TIPS creation.

Portal Hypertension

West China Hospital30 participantsStarted Feb 2017

Chengdu, Sichuan, China

Virtual Hepatic Venous Pressure Gradient (vHVPG) With CT Angiography (CHESS1601)

A Novel Approach for Transjugular Intrahepatic Portocaval Shunt Creation Using Real-time Three Dimensional Roadmap

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