Heart Disease Clinical Trials in Massachusetts

Showing 161-180 of 530 trials

Thromboxane Receptor Antagonist to Improve Endothelial Function

NCT03962855

This study evaluates whether addition of the thromboxane receptor antagonist to chronic aspirin therapy improves endothelial function and reduces non-platelet thromboxane generation in patients with established cardiovascular disease. Half of participants will receive ifetroban and the other half will receive matching placebo for the 4 week study period.

Cardiovascular DiseasesVascular Dilation

Jeffrey Rade57 participantsStarted Sep 2019

Worcester, Massachusetts, United States

COMPLETEDNA14 miles

ILUMIEN IV: OPTIMAL Percutaneous Coronary Intervention (PCI)

NCT03507777

The objective of this prospective, single-blind clinical investigation is to demonstrate the superiority of an Optical Coherence Tomography (OCT)-guided stent implantation strategy as compared to an angiography-guided stent implantation strategy in achieving larger post-PCI lumen dimensions and improving clinical cardiovascular outcomes in patients with high-risk clinical characteristics and/or with high-risk angiographic lesions.

Coronary Artery DiseaseCoronary StenosisAtherosclerosis+3 more

Abbott Medical Devices2,487 participantsStarted May 2018

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Burlingame, California, United States +87 more locations

Thromboxane Receptor Antagonist to Improve Endothelial Function

ILUMIEN IV: OPTIMAL Percutaneous Coronary Intervention (PCI)

Heart Disease Trials in Other Cities

Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

Allogeneic Valve Transplantation

Remote-delivered MBCT for SCAD Survivors

Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models

Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF

Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator

TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)

Physiologic Pacing Registry

Percutaneous RVAD to Preemptively Treat Right Heart Failure Post-LVAD

Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Apple Watch Heart Failure Study

Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)

AZD8601 Study in CABG Patients

Acorai Machine Learning Generalization (MLG) Study

Alleviate-HF-2 Study

Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction

Other Conditions in Massachusetts