Heart Disease Clinical Trials in Massachusetts

Showing 221-240 of 258 trials

Physiological Response to Exercise: Sensor Evaluation at Specified Exertions

NCT01229137

Assessment of sensor parameter in patients with heart failure.

Boston Scientific Corporation71 participantsStarted Jun 2011

Jonesboro, Arkansas, United States • Sacremento, California, United States • Danbury, Connecticut, United States +11 more locations

COMPLETEDPHASE214 miles

Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)

NCT00642174

This trial is designed as a phase 2 randomized, double-blind double dummy, active comparator controlled, two-period two-arm crossover study to enroll 40 patients across multiple centers. The study will compare platelet function following a prasugrel loading dose and 1 week of prasugrel maintenance therapy with high-dose clopidogrel loading dose and 1 week of high-dose clopidogrel maintenance therapy in patients with drug treated type 2 diabetes mellitus who have coronary artery disease. Various assays of platelet function will be used in this study. Platelet function will be studied using the following assays: Accumetrics VerifyNowTM P2Y12, Light Transmittance Aggregometry (LTA), Vasodilator-associated stimulated phosphoprotein (VASP), and Thromboelastography (TEG)-platelet mapping.

Diabetes MellitusCoronary Artery Disease

Eli Lilly and Company35 participantsStarted Apr 2008

Jacksonville, Florida, United States • Worcester, Massachusetts, United States • New York, New York, United States +1 more locations

Physiological Response to Exercise: Sensor Evaluation at Specified Exertions

Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)

Heart Disease Trials in Other Cities

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

HIV and Cardiovascular Risk

TAXUS ATLAS: TAXUS Liberté™-SR Stent for the Treatment of de Novo Coronary Artery Lesions

SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)

Mind-body Interventions in Cardiac Patients

PROSPECT: An Imaging Study in Patients With Unstable Atherosclerotic Lesions

The WOMEN Study: What is the Optimal Method for Ischemia Evaluation in WomeN?

Study of the Safety and Efficacy of Apadenoson for Detection of Myocardial Perfusion Defects Using SPECT MPI

Registry Experience at the Washington Hospital Center, Des - Taxus Liberte Versus Xience V

A Study of the Safety and Tolerance of Regadenoson in Subjects With Renal Impairment

PLASMA Trial: A Dose-Response Study of A-002 In Subjects With Stable Coronary Artery Disease

Study to Assess the Safety and Efficacy of CD-NP in the Treatment of Patients With Acute Decompensated Heart Failure

A-priori Versus Provisional Heparin on Radial Artery Occlusion After Transradial Coronary Angiography and Patent Hemostasis

Safety and Efficacy Study of KAI-9803 to Treat Subjects With ST Elevation Myocardial Infarction [Heart Attack]

Comparison of Prasugrel and Clopidogrel in Very Elderly and Non-Elderly Patients With Stable Coronary Artery Disease

Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation

Comparison of Prasugrel and Clopidogrel in Low Body Weight Versus Higher Body Weight With Coronary Artery Disease

Study Evaluating How Patients With Acute Coronary Syndrome Are Managed During 2 Years After Discharge

Other Conditions in Massachusetts