Heart Disease Clinical Trials in Denver

Showing 361-380 of 427 trials

A Thyroid Hormone Analog to Fight Heart Failure: Phase II Trial (DITPA)

NCT00032643

Congestive heart failure (CHF) affects 4-5 million Americans, and its prevalence is predicted to increase over the next few decades. Thyroid hormone has unique actions which make it a novel and potentially useful agent for treatment of CHF. Due to possible adverse affects of thyroid hormone, there is interest in developing analogs with fewer undesirable side effects. 3,5- diiodothyropropionic acid (DITPA) has been shown to improve diastolic function in both animal models and a recently completed double-blind placebo controlled trial in 19 humans. The goal of the proposed Phase II study is to show safety and demonstrate a medication of efficacy of DITPA needed in patients with CHF. This study is a prerequisite for a larger Phase III trial which would determine whether mortality is improved with DITPA. To better define the appropriate doses, prior to the Phase II study we will conduct an initial pharmacokinetic study.

Congestive Heart Failure

US Department of Veterans Affairs150 participantsStarted Jun 2004

Tucson, Arizona, United States • West Los Angeles, California, United States • Denver, Colorado, United States +4 more locations

TERMINATEDPhase 4< 1 mile

Rapid Assessment of Bedside BNP In Treatment of Heart Failure (RABBIT)

NCT00206856

To determine the clinical utility of using the Triage® BNP Test to guide therapy in outpatients with heart failure

Heart Failure

Abbott RDx Cardiometabolic720 participantsStarted Jul 2003

Scottsdale, Arizona, United States • San Diego, California, United States • San Francisco, California, United States +26 more locations

A Thyroid Hormone Analog to Fight Heart Failure: Phase II Trial (DITPA)

Rapid Assessment of Bedside BNP In Treatment of Heart Failure (RABBIT)

Heart Disease Trials in Other Cities

Exercise Training Program to Improve Clinical Outcomes in Individuals With Congestive Heart Failure

SPIRIT IV Clinical Trial: Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System

TAXUS PERSEUS Workhorse

OMNI Study--Assessing Therapies in Medtronic Pacemaker, Defibrillator, and Cardiac Resynchronization Therapy Devices.

Drug Compliance and Quality of Life in Patients With Heart Failure Dosed With Either Once-daily or Twice-daily Coreg

Efficacy and Safety in Patients With Type 2 Diabetes Mellitus, Cardiovascular Disease and Hypertension

Radial Artery Versus Saphenous Vein Grafts in Coronary Artery Bypass Surgery

Attain Success Clinical Trial

Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study)

Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Ischemic Heart Failure.

Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo.

A Randomized Controlled Trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly People

OVATIO CRT and SITUS OTW LV Lead Post Approval Study

Drug Eluting Stent Registry of Thrombosis

Clinical Evaluation of the Physiological Diagnosis Function in the PARADYM CRT Device

Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure

Computed Tomography Dose Reduction Using Sequential or Fast Pitch Sprial Technique

Study Evaluating How Patients With Acute Coronary Syndrome Are Managed During 2 Years After Discharge

Other Conditions in Denver