Heart Disease Clinical Trials in Cleveland

Showing 61-80 of 500 trials

Sternal Plating High Risk

NCT06660186

Participants are being invited to participate in a research study at University Hospitals because they have heart disease and are scheduled for open heart surgery. Currently, UH cardiac surgeons close the sternum (or breastbone) after a sternotomy (procedure that allows a doctor to reach the heart and blood vessels) with either a rigid plate fixation Sternal Plate or a Wire Cerclage. However, the study team would like to further evaluate these two techniques. Any volunteer over the age of 18 who is at an increased risk for developing sternal wound complications may be eligible to participate.

Heart Diseases

University Hospitals Cleveland Medical Center250 participantsStarted Feb 2026

Cleveland, Ohio, United States

RECRUITINGNA< 1 mile

Assessment of CCM in HF With Higher Ejection Fraction

NCT05064709

The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤70%.

Heart FailureHeart Failure With Preserved Ejection FractionHeart Failure With Mid Range Ejection Fraction+2 more

Impulse Dynamics1,500 participantsStarted Feb 2022

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Mesa, Arizona, United States +109 more locations

Sternal Plating High Risk

Assessment of CCM in HF With Higher Ejection Fraction

Heart Disease Trials in Other Cities

Comparative Imaging Assessment of Valvular Heart Disease

Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study

STeroids to REduce Systemic Inflammation After Infant Heart Surgery

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Vascular Lab Resource (VLR) Biorepository

PIONEER III Trial to Assess Safety and Efficacy of the BuMA Supreme™ Drug Coated Coronary Stent in Patients With Coronary Disease

A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure

A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)

Sapphire 3 CTO Study

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)

Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure

Equity in Modifying Plaque Of WomEn With UndeRtreated Calcified Coronary Artery Disease

Impact of Barostimulation on Hemodynamics in Adults With Heart Failure

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation

Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease

Other Conditions in Cleveland