Heart Disease Clinical Trials in Chicago

Showing 261-280 of 511 trials

SUSTAIN-IT: Sustaining Quality of Life of the Aged: Heart Transplant or Mechanical Support?

NCT02568930

The purpose of this study is to compare health-related quality of life (HRQOL) outcomes in older (60-80 years) advanced heart failure (HF) patients who undergo heart transplantation (HT) or mechanical circulatory support (MCS) as a permanent implant (i.e., destination therapy \[DT\]) and their caregivers. Our study will contribute to better patient-centered care of older advanced HF patients and their caregivers, by informing decision making and guiding strategies to enhance post-operative HRQOL.

Heart Failure

Northwestern University694 participantsStarted Oct 2015

Birmingham, Alabama, United States • Orlando, Florida, United States • Chicago, Illinois, United States +10 more locations

COMPLETEDPhase 32.2 miles

Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction

NCT02929329

The purpose of this study is to determine if treatment with omecamtiv mecarbil when added to standard of care is well tolerated and superior to placebo in reducing the risk of cardiovascular death or heart failure events in adults with chronic heart failure with reduced ejection fraction (HFrEF).

Heart Failure

Cytokinetics8,256 participantsStarted Jan 2017

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Birmingham, Alabama, United States +1030 more locations

SUSTAIN-IT: Sustaining Quality of Life of the Aged: Heart Transplant or Mechanical Support?

Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction

Heart Disease Trials in Other Cities

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Safety and Tolerability Study of AZD4831 in Patients With Heart Failure.

EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)

St. Jude Medical Product Longevity and Performance (SCORE) Registry

Mindful Hearts Study: Mindfulness to Reduce Stress

Restore EF Observational Study

Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion

Randomized Endo-Vein Graft Prospective

Heart Sounds Registry

COBRA PZF™ Coronary Stent for Early Healing, Thrombus Inhibition, Endothelialization and Avoiding Long-Term DAPT

Rheos System for the Treatment of HFpEF Heart Failure

Interactions Between HIV Protease Inhibitors and Calcium Channel Blockers

A Clinical Trial to Assess the SYNERGY 48 mm Stent System for the Treatment of Atherosclerotic Lesion(s)

Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-142

Continued Access Protocol for the Evaluation of the OPTIMIZER Smart System

Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event

A Single Arm Trial With Resolute Onyx in ONE-Month DAPT for High-Bleeding Risk Patients Who Are Considered One-Month Clear (Onyx ONE Clear)

A Study of CK-1827452 Infusion in Stable Heart Failure

Other Conditions in Chicago