Heart Disease Clinical Trials in Atlanta

Showing 281-300 of 398 trials

Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure

NCT01644331

The primary objective of this study is to compare the effects of oral Tolvaptan vs. placebo as an adjunct to fixed dose IV furosemide on dyspnea relief in patients with acute decompensated heart failure The primary hypothesis is that the addition of oral Tolvaptan to fixed dose furosemide will be more effective at relieving dyspnea than fixed dose furosemide alone

Heart FailureDyspnea

Duke University257 participantsStarted Oct 2012

Aurora, Colorado, United States • Atlanta, Georgia, United States • Gainesville, Georgia, United States +15 more locations

TERMINATEDPhase 4< 1 mile

Naltrexone/Bupropion Cardiovascular Outcomes Study

NCT02638129

The purpose of this study is to evaluate cardiovascular (CV) safety of naltrexone hydrochloride (HCl) and bupropion HCl extended release combination (NB) compared with placebo and rule out excess risk of major adverse cardiovascular events (MACE) when given in combination with standard of care in overweight and obese participants with documented history of CV disease.

ObesityCardiovascular Diseases

Orexigen Therapeutics, Inc67 participantsStarted Jan 2016

Alexander City, Alabama, United States • Auburn, Alabama, United States • Birmingham, Alabama, United States +136 more locations

Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure

Naltrexone/Bupropion Cardiovascular Outcomes Study

Heart Disease Trials in Other Cities

Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass

Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)

Get Going: Accelerometer-Based Intervention to Promote Physical Activity in Frail Older Adults

Pharmacodynamic and Pharmacokinetic Study of BiDil Extended-release Capsules and Commercial BiDil Tablets

Randomized, Double-Blind, Placebo Controlled Study of the Short Term Clinical Effects of Tolvaptan in Patients Hospitalized for Worsening Heart Failure With Challenging Volume Management

Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients

A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery

Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)

A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease

Safety Study of the Ventricular Partitioning Device (VPD) Implant System in Heart Failure Patients

Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery Disease

Evaluation of Vepoloxamer in Chronic Heart Failure

NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation

A Dose-Defining Study of CXL-1020 in Patients With Systolic Heart Failure

Educational Program for Various Health Literacy Levels to Improve the Health of Individuals With Heart Failure

Assessment of Catheter-based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement

Efficacy of Remodulin in Adults With Congenital Heart Disease (ACHD) and Pulmonary Hypertension

A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure

Other Conditions in Atlanta