Diabetes Clinical Trials

Showing 5141-5160 of 7,874 trials

Exercise to Reduce Obesity in Spinal Cord Injury

NCT00270855

The purpose of this proposal was to evaluate and compare the health benefits of using upper extremity exercise versus functional electrical stimulation for lower extremity exercise. It was our hypothesis that both Functional Electrical Stimulation Leg Cycle Ergometry (FES LCE) exercise and voluntary Arm Crank Ergometry (ACE) upper extremity exercise would increase whole body energy expenditure, thereby increasing muscle mass, insulin sensitivity, glucose effectiveness and improving lipid profiles in adults with paraplegia.

Diabetes MellitusObesityParaplegia+2 more

VA Office of Research and Development29 participantsStarted May 2008

Richmond, Virginia, United States

COMPLETEDNA

Integration of Continuous Glucose Monitoring Into a BiHormonal Closed-Loop Artificial Pancreas

NCT01161862

The investigators hypothesize that our closed-loop glucose-control system can provide BG control in subjects with type 1 diabetes using the estimated BG signal from a CGM as the input signal to the controller.

Diabetes Mellitus

Boston University Charles River Campus24 participantsStarted Jul 2010

Boston, Massachusetts, United States

TERMINATEDPhase 2

TRX4 Monoclonal Antibody in Type 1 Diabetes (T1 DM)

NCT00451321

The purpose of this study is to optimize several multi-dose regimens of otelixizumab, determine the highest biologically active dose, evaluate biomarkers and surrogates of efficacy, and to evaluate the effects of each multi-dose regimen of otelixizumab against standard safety and efficacy parameters.

Diabetes Mellitus, Type 1

GlaxoSmithKline88 participantsStarted Jul 2006

Birmingham, Alabama, United States • Walnut Creek, California, United States • Aurora, Colorado, United States +14 more locations

Exercise to Reduce Obesity in Spinal Cord Injury

Integration of Continuous Glucose Monitoring Into a BiHormonal Closed-Loop Artificial Pancreas

TRX4 Monoclonal Antibody in Type 1 Diabetes (T1 DM)

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