Diabetes Clinical Trials

Showing 4341-4360 of 7,874 trials

Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes

NCT03848533

Melatonin is a hormone that regulates the circadian cycle in addition to having an antioxidant effect. Patients with prediabetes state, has a deregulation of glucose metabolism and an overproduction of reactive oxygen species caused by levels of hyperglycemia that generate DNA modification in pancreatic beta cells, which leads to apoptosis and a deficient production of insulin. The administration of metformin and melatonin could be a possibility to treat and reverse the prediabetic state decreasing the glycemic levels and reactive oxygen species production.

PreDiabetes

University of Guadalajara42 participantsStarted Aug 2019

Guadalajara, Jalisco, Mexico

COMPLETEDNA

Supporting Parents of Young Children With Type 1 Diabetes in Closed-Loop System

NCT03354286

This study will examine the impact of a closed-loop insulin delivery system intervention on health and psychological outcomes in families with young children with Type 1 Diabetes (T1D).

Type 1 Diabetes Mellitus

Stanford University26 participantsStarted Nov 2017

Palo Alto, California, United States

Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes

Supporting Parents of Young Children With Type 1 Diabetes in Closed-Loop System

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Collection of Human Liver Biopsy and Whole Blood Samples From T1DM, TP or PP Patients for Potential Use for Insulin Producing Cells in Future Clinical Studies

Effects of an Amino Acid and Chromium-picolinate Containing Drink on Glucose Metabolism

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Clinical Usability of Nasal Glucagon in Treatment of Hypoglycemia in Children and Adolescents

Comparing the Accuracy of Different Blood Glucose Monitoring Systems (CGM and FGM)

Extracorporeal Shock Wave Therapy on Diabetes Related Frozen Shoulder

Changes in Insulin Sensitivity After Weight Loss

A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)

Clinical Startup of the 670G Closed Loop Insulin Delivery System

Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes

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A Study Comparing the Effects and Safety of Dulaglutide With Glimepiride in Type 2 Diabetes Mellitus

Network-based Approach in Type 2 Diabetes and Its Cardiovascular Risk

A Study to Compare the Effect of a Double Dose of Two Long-acting Insulin Therapies in Participants With Type 2 Diabetes

Acute Mycoprotein Effect on Glycaemic Control in South Asians