Diabetes Clinical Trials

Showing 3301-3320 of 7,874 trials

Personalized Glucose Optimization Through Nutritional Intervention

NCT03708419

Maintaining well-controlled blood glucose concentrations is essential in the prevention of chronic cardiometabolic diseases. The blood glucose response to dietary and/or lifestyle patterns may vary between individuals. Insulin resistance in specific metabolic organs such as skeletal muscle, adipose tissue or the liver may underlie differential blood glucose responses. This dietary intervention study aims to obtain insight into the metabolic and lifestyle determinants of postprandial blood glucose responses, and to establish the effect of macronutrient manipulation of a 12-week dietary intervention on blood glucose homeostasis in metabolically different subgroups an its relationship to physical and mental performance and well-being.

ObesityPre-diabeticType 2 Diabetes Mellitus

Maastricht University Medical Center242 participantsStarted Jun 2018

Maastricht, Netherlands • Wageningen, Netherlands

COMPLETEDPhase 3

A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes

NCT03987919

The reason for this study is to compare the effect of the study drug tirzepatide to semaglutide on blood sugar levels in participants with type 2 diabetes. The study will last approximately 47 weeks and may include about 12 visits.

Type 2 Diabetes

Eli Lilly and Company1,879 participantsStarted Jul 2019

Birmingham, Alabama, United States • Sheffield, Alabama, United States • Huntington Park, California, United States +124 more locations

Personalized Glucose Optimization Through Nutritional Intervention

A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes

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