Crohn's Disease Clinical Trials

Showing 781-800 of 1,088 trials

Fecal Calprotectin Collection Protocol

NCT03143517

The primary objective is to obtain stool samples from subjects diagnosed with , and displaying signs and/or symptoms of IBD and/or IBS will be evaluated in this study. Eligible subjects require a diagnostic colonoscopy with possible biopsy and clinical evaluation.

Inflammatory Bowel DiseasesIrritable Bowel SyndromeUlcerative Colitis+10 more

DiaSorin Inc.240 participantsStarted Apr 2017

Dothan, Alabama, United States • Little Rock, Arkansas, United States • Mission Hills, California, United States +10 more locations

COMPLETED

Proteomic Analysis of Crohn's Disease Macrophages in Response or Not to AIEC

NCT03404557

The M2iSH laboratory showed with two previous clinical trials that Crohn's Disease (CD) macrophages present i) a defect to control Adherent-Invasive Escherichia coli (AIEC) infection related to polymorphisms associated with CD; ii) a CD - specific cytokine secretion profile after an AIEC infection and intestinal inflammation dependent; iii) a modification of the response of CD macrophages at a basal state and after the AIEC infection. These results consolidate the hypothesis of a defect specific to CD macrophages. That's why, the primary purpose of this study is to realize a proteomic analysis of macrophages of CD patients infected or not with AIEC and to compare them to Ulcerative Colitis (UC) patients and healthy volunteers.

Crohn's DiseaseUlcerative Colitis

University Hospital, Clermont-Ferrand88 participantsStarted Jan 2018

Clermont-Ferrand, France

Fecal Calprotectin Collection Protocol

Proteomic Analysis of Crohn's Disease Macrophages in Response or Not to AIEC

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