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Clareo Health | Colorectal Cancer Clinical Trials in Pittsburgh | 201 Studies

Clinical Trials Colorectal CancerPittsburgh

Colorectal Cancer Clinical Trials in Pittsburgh

Find 201 clinical trials for colorectal cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Pittsburgh

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 201 trials

TerminatedChemokine-Modulatory Regimen for Recurrent Resectable Colorectal CancerDetermine the safety of a combination of IFN, celecoxib, and rintatolimod for patients with recurrent colorectal cancer.NCT01545141·Pittsburgh, Pennsylvania CompletedCPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced CancersThis is a Phase 1/1b open-label, dose escalation and dose expansion study of CPI-006, a humanized monoclonal antibody (mAb) targeting the CD73 cell-surface ectonucleotidase in…NCT03454451·Tucson, Arizona and 26 others

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Data from ClinicalTrials.govTerms

RecruitingKO-2806 Monotherapy and Combination Therapies in Advanced Solid TumorsThis first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyltransferase inhibitor (FTI), as a monotherapy and in combination, in…NCT06026410·Phoenix, Arizona and 37 others

CompletedStudy of the MUC1 Peptide-Poly-ICLC Adjuvant Vaccine in Individuals With Advanced Colorectal AdenomaThe purpose of this study is to evaluate the immune response to MUC1 - poly-ICLC vaccine, an investigational or study vaccine.NCT00773097·Pittsburgh, Pennsylvania

CompletedRadiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the RectumRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00006366·Birmingham, Alabama and 234 others

CompletedA Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal CancerThis is an international multi-center, prospective, open-label, randomized, adaptive design phase 3 trial of the cancer stem cell pathway inhibitor napabucasin plus standard…NCT02753127·Birmingham, Alabama and 210 others

Active not recruitingTesting the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and IntestinesThis phase I trial investigates the best dose, possible benefits and/or side effects of BAY 1895344 in combination with FOLFIRI in treating patients with stomach or intestinal…NCT04535401·Duarte, California and 9 others

CompletedGenetic Study of Young Patients With Colorectal CancerRATIONALE: Identifying gene mutations (microsatellite instability) may allow doctors to plan effective treatment for patients who develop colorectal cancer at an early age.NCT00044967·Mobile, Alabama and 72 others

CompletedGlycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.NCT05259696·La Jolla, California and 12 others

CompletedAflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based RegimenThe main objective of the study was to evaluate the effectiveness of aflibercept (versus placebo) in increasing the overall survival in participants with metastatic colorectal…NCT00561470·Birmingham, Alabama and 220 others

TerminatedA Study of SGN-CD228A in Advanced Solid TumorsThis trial will study SGN-CD228A to find out whether it is an effective treatment for different kinds of cancer.NCT04042480·Birmingham, Alabama and 13 others

RecruitingEvaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer SurvivorsThis phase III trial evaluates whether a web-based intervention called Current Together after Cancer (CTAC) works to increase the number of patients with surgically removed…NCT07018869·Anchorage, Alaska and 383 others

RecruitingA Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal CancerThis study is being done to find out if tucatinib with other cancer drugs works better than standard of care to treat participants with HER2 positive colorectal cancer.NCT05253651·Glendale, Arizona and 365 others

Active not recruitingM6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryThis phase I trial studies the side effects and best dose of M6620 and irinotecan hydrochloride in treating patients with solid tumors that have spread to other places in the body…NCT02595931·Los Angeles, California and 22 others

CompletedOctreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal CancerRATIONALE: Octreotide may be effective in preventing or controlling diarrhea in patients who are undergoing chemoradiotherapy for anal or rectal cancer.NCT00075868·Mobile, Alabama and 111 others

TerminatedA Study of SGN-STNV in Advanced Solid TumorsThis trial will look at a drug called SGN-STNV to find out whether it is safe for patients with solid tumors. It will study SGN-STNV to find out what its side effects are.NCT04665921·Los Angeles, California and 17 others

TerminatedA Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid TumorsThis research study is studying a new drug, NC410, as a possible treatment for advanced or metastatic solid tumors.NCT04408599·Bethesda, Maryland and 4 others

RecruitingTesting the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable CancersThis phase I trial tests the safety, side effects, and best dose of ZEN003694 in combination with the usual treatment with capecitabine in treating patients with cancer that has…NCT05803382·Irvine, California and 21 others

RecruitingStudy of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid TumorsThis study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patients with KRAS G12C-mutated…NCT06128551·Duarte, California and 55 others

CompletedA Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)This was an open-label, nonrandomized, Phase 1/2 study designed to determine the safety, tolerability, and efficacy of epacadostat when given in combination with pembrolizumab and…NCT03085914·Phoenix, Arizona and 15 others

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