Colorectal Cancer Clinical Trials in Pittsburgh

Showing 221-240 of 342 trials

Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal Cancer

NCT01960023

The FC-7 study is designed as an open label, single arm, Phase I/II dose-escalation study evaluating the combination of neratinib and cetuximab in patients with metastatic colorectal cancer primary tumor that is "quadruple wild-type " (wild-type KRAS, NRAS, BRAF, PIK3CA). The primary aim in the Phase I portion of this study is to determine the safety and tolerability of the two-drug combination. The primary aim of the Phase II part is to determine the overall objective response rate (complete and partial responses) by Response Evaluation Criteria in Solid Tumors (RECIST 1.1). Patients will receive concurrent therapy with cetuximab (400 mg/m2 IV loading dose followed by 250 mg/m2 IV weekly), and neratinib.

Colorectal Cancer

NSABP Foundation IncStarted Oct 2013

Gainesville, Florida, United States • Orlando, Florida, United States • Boise, Idaho, United States +9 more locations

COMPLETEDPhase 1/2< 1 mile

Safety Study of 90Y-hMN14 to Treat Colorectal Cancer

NCT00040599

The purpose of this trial is to determine the safety of 90Y-hMN14 at different dose levels in the treatment of colorectal cancer.

Colorectal CancerColon CancerRectal Cancer+3 more

Gilead Sciences72 participantsStarted Jan 2000

Newport Beach, California, United States • Washington D.C., District of Columbia, United States • St. Petersburg, Florida, United States +7 more locations

Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal Cancer

Safety Study of 90Y-hMN14 to Treat Colorectal Cancer

Colorectal Cancer Trials in Other Cities

Detecting Activity to Support Healing

Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum

Longitudinal Performance of Epi proColon

Blood and Stool Sample Collection in Subjects Participating in Colorectal Cancer Screening: Act Bold

Sample Collection Study for the CellMax Life Circulating Tumor Cell and Circulating Tumor DNA Platforms for the Early Detection of Colorectal Cancer and Adenomas

A Study Assessing Perfusion Outcomes With PINPOINT® Near Infrared Fluorescence Imaging in Low Anterior Resection

Open-Label Phase IIb Efficacy Trial of Cancer Macrobeads Compared to Best Supportive Care in Colorectal Cancer Patients

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

Phase 2a Study of BAX69 and 5-FU/Leucovorin or Panitumumab Versus Standard of Care in Subjects With Metastatic Colorectal Cancer

The National CT Colonography Trial

Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)

5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer

Plasma-based Colorectal Cancer Screening Research & Development

Comparison of Adenoma Detection Rate With ENDOCUFF VISION® vs. G-EYE®

Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors

A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors

First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation

EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options

Other Conditions in Pittsburgh