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Clareo Health | Colorectal Cancer Clinical Trials in Massachusetts | 399 Studies

Clinical Trials Colorectal CancerMassachusetts

Colorectal Cancer Clinical Trials in Massachusetts

Find 399 clinical trials for colorectal cancer near Massachusetts. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 321-340 of 399 trials

RecruitingA Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid TumorsThis study will assess the safety and efficacy of VS-7375 alone and in combination in patients with advanced solid tumors harboring a KRAS G12D-mutation.NCT07020221·Los Angeles, California and 13 others TerminatedA Study of SGN-STNV in Advanced Solid TumorsThis trial will look at a drug called SGN-STNV to find out whether it is safe for patients with solid tumors. It will study SGN-STNV to find out what its side effects are.NCT04665921·Los Angeles, California and 17 others

Colorectal Cancer Trials in Other Cities

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Data from ClinicalTrials.govTerms

CompletedGene Therapy in Treating Patients With CancerRATIONALE: Inserting a gene that has been created in the laboratory into a person's white blood cells may make the body build an immune response to kill cancer cells.NCT00004178·Boston, Massachusetts

CompletedOnline Trial Examining Validity of the Shared Decision Making Process Survey With Video VignettesThis study will recruit subjects online and randomly assigned them to one of four arms.NCT04317274·Boston, Massachusetts

Active not recruitingA Study of Botensilimab and Balstilimab for the Treatment of Colorectal CancerThis is an open-label, Phase 2, multicenter study to evaluate the efficacy, safety, tolerability, and pharmacokinetic profiles of botensilimab as monotherapy and in combination…NCT05608044·Scottsdale, Arizona and 64 others

CompletedCombination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With Advanced or Metastatic Colorectal Cancer That Has Been Previously TreatedRandomized phase III trial to compare the effectiveness of combination chemotherapy with or without bevacizumab in treating patients who have advanced or metastatic colorectal…NCT00025337·Boston, Massachusetts

TerminatedChemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal CancerThe primary objective of this study is to evaluate the safety and efficacy of Irinotecan Bead in combination with intravenous chemotherapy versus intravenous chemotherapy alone in…NCT00816777·Aurora, Colorado and 2 others

RecruitingStudy of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid TumorsThis study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patients with KRAS G12C-mutated…NCT06128551·Duarte, California and 55 others

RecruitingA Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal CancerThe purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of…NCT07284849·Mobile, Alabama and 279 others

CompletedDNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)The primary objective of this study, DELFI-L101, is to train and test classifiers for lung cancer detection using the DELFI assay and other biomarker and clinical features.NCT04825834·Homewood, Alabama and 56 others

CompletedPhase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid TumorsThis is a Phase 1/2, open-label, first-in-human (FIH) study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary…NCT03037385·Phoenix, Arizona and 70 others

TerminatedA Study to Investigate LYL845 in Adults With Solid TumorsThis is an open-label, multi-center, dose-escalation study with expansion cohorts, designed to evaluate the safety and anti-tumor activity of LYL845, an epigenetically…NCT05573035·Sacramento, California and 17 others

RecruitingStudy of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of RMC-5127 as a monotherapy and in combination with…NCT07349537·New Haven, Connecticut and 8 others

CompletedProspective Analysis of Hypersensitivity Reactions to OxaliplatinThis research study will examine how often hypersensitivity, or allergic reactions, occur in patients receiving the chemotherapy medication oxaliplatin.NCT00831571·Boston, Massachusetts

RecruitingMOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid TumorsThe main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in…NCT06586515·Duarte, California and 51 others

RecruitingPhase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid TumorsPhase I Study, a master protocol to investigate TCR-Engineered T cells recognizing KRAS mutations in adult subjects with Unresectable, Advanced, and/or Metastatic Solid Tumors.NCT06218914·Duarte, California and 17 others

RecruitingEpacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal CancerThe purpose of this research study is to evaluate epacadostat when given with routine radiation therapy and chemotherapy (capecitabine and oxaliplatin) to treat rectal cancer…NCT03516708·Orange, California and 3 others

TerminatedSafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal StudyA randomized trial to assess the safety and effectiveness of the Colovac in providing temporary protection of the anastomosis in subjects undergoing lower anterior resection for…NCT05010850·Los Angeles, California and 15 others

CompletedPhase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal CancerThis phase 1/2, multi-center, randomized, double-blind, placebo-controlled trial is designed to evaluate the efficacy and safety of AMG 655 when combined with mFOLFOX6 and…NCT00625651·Hot Springs, Arkansas and 60 others

RecruitingA Study of Novel Study Interventions and Combinations in Participants With Colorectal CancerThe main purpose of this study is to evaluate the safety and efficacy of novel study interventions and combinations in participants with Colorectal Cancer (CRC).NCT06792695·Scottsdale, Arizona and 75 others

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Other Conditions in Massachusetts

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma