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Clareo Health | Colorectal Cancer Clinical Trials in Massachusetts | 399 Studies

Clinical Trials Colorectal CancerMassachusetts

Colorectal Cancer Clinical Trials in Massachusetts

Find 399 clinical trials for colorectal cancer near Massachusetts. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 241-260 of 399 trials

CompletedA Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid TumorsThis is a Phase 1 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph-CpG-7909\] plus a mixture of…NCT04853017·Duarte, California and 9 others RecruitingSolid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell ManufacturingObjective: To collect information on how often a solid tumor cancer might lose the Human Leukocyte Antigen (HLA) by next generation sequencing and perform apheresis to collect…NCT04981119·Gilbert, Arizona and 15 others

Colorectal Cancer Trials in Other Cities

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Data from ClinicalTrials.govTerms

CompletedVaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the LiverRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00033748·Anniston, Alabama and 74 others

Active not recruitingDurvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung CancerThis randomized phase II trial studies the side effects of durvalumab and tremelimumab and to see how well they work with or without high or low-dose radiation therapy in treating…NCT02888743·Phoenix, Arizona and 41 others

TerminatedA Study of AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary CancerThis study is to define the safety profile and to determine the Maximal tolerated dose regimen and preliminary efficacy of AbGn-107 administered every 14 days (Q2W regimen) or 28…NCT02908451·Phoenix, Arizona and 8 others

CompletedPanitumumab in Cetuximab Refractory KRAS Wild-Type Colorectal CancerThe purpose of this research study is to learn whether panitumumab helps treat colorectal cancer in participants who have not responded to treatment with cetuximab.NCT00842257·Boston, Massachusetts and 2 others

CompletedImproving the Frequency of Colonoscopy in Patients With a Previous Colorectal PolypRATIONALE: Receiving a reminder letter from their doctor may increase the frequency of colonoscopy in patients who have had a colorectal polyp removed.NCT00397969·Boston, Massachusetts and 1 other

CompletedFluorouracil and Leucovorin With or Without Oxaliplatin in Treating Patients With Recurrent Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00016198·Tucson, Arizona and 73 others

CompletedA Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)This is a Phase 1/2, open label study. Phase 1 consists of 2 parts.NCT02327078·Birmingham, Alabama and 23 others

RecruitingStudy of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid TumorsThe investigational drug to be studied in this protocol, BCA101, is a first-in-class compound that targets both EGFR with TGFβ.NCT04429542·La Jolla, California and 19 others

TerminatedA Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid TumorsThis is an open-label, multicenter, First-In-Human (FIH), Phase 1a/1b study of PY159 in subjects with locally advanced (unresectable) and/or metastatic solid tumors that are…NCT04682431·Los Angeles, California and 16 others

CompletedPressure-enabled Delivery in Radioembolization (TriNav Study)The purpose of the study is to determine if the type of catheter used in the mapping procedure prior to radioembolization improves the delivery of radioactivity to tumor(s) in…NCT05128032·Boston, Massachusetts and 1 other

CompletedA Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors* To evaluate the safety and tolerability of escalating doses of ERAS-601 when administered as a monotherapy and in combination with other cancer therapies in study participants…NCT04670679·Birmingham, Alabama and 13 others

CompletedA Phase 2 Study of Lamivudine in Patients With p53 Mutant Metastatic Colorectal CancerThis research study is studying a drug as a possible treatment for p53 mutant metastatic colorectal cancer. The drug involved in this study is: -LamivudineNCT03144804·Boston, Massachusetts

CompletedStudy of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 GeneOpen-label, Phase I-II, first-in-human (FIH) study for A166 monotherapy in HER2-expressing or amplified patients who progressed on or did not respond to available standard…NCT03602079·Sarasota, Florida and 9 others

TerminatedA Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal CancerThe study will combine a new investigational drug with standard anti-cancer drugs for the treatment of advanced colorectal cancer.NCT00040391·Little Rock, Arkansas and 27 others

Active not recruitingTTX-080 HLA-G Antagonist in Subjects With Advanced CancersTTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase 2 dose of TTX-080 monotherapy…NCT04485013·Tucson, Arizona and 40 others

RecruitingPost-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal ResectionsThe purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular reloads (hereafter…NCT07351071·New Haven, Connecticut and 9 others

RecruitingLYL273 for Patients With Relapsed or Refractory mCRCThis is a Phase 1/2 open-label, multicenter study evaluating the safety and efficacy of LYL273 in participants with relapsed or refractory metastatic colorectal cancer.NCT05319314·Duarte, California and 3 others

Active not recruitingA Study of PARG Inhibitor IDE161 in Participants With Advanced Solid TumorsThe purpose of this study is to characterize the safety, tolerability, and efficacy of IDE161 as a single agent and in combination with pembrolizumab.NCT05787587·Phoenix, Arizona and 26 others

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Other Conditions in Massachusetts

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma