Colorectal Cancer Clinical Trials in Colorado

Showing 101-120 of 152 trials

Anti-PD-1 +/- RT for MSI-H Solid Tumors

NCT04001101

To determine if the out-of-field ORR is improved with the addition of radiation therapy to anti-PD-1 for patients with MSI-H/dMMR metastatic solid tumors. Determine the rates of in-field tumor control, disease control (stable disease, partial response, complete response), durability of disease response, progression-free survival, overall survival, and to assess quality of life and toxicity. Determine the chronology and profile of the radiation-associated immune response.

Microsatellite Instability HighMismatch Repair DeficiencyColorectal Cancer

University of Colorado, DenverStarted Oct 2019

Denver, Colorado, United States

COMPLETEDPHASE250 miles

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

NCT01298570

This randomized (2:1), multi-center, placebo-controlled, phase II efficacy study is designed to compare PFS between regorafenib + FOLFIRI chemotherapy (ARM A) versus placebo + FOLFIRI (ARM B) in patients with mCRC previously treated with a FOLFOX regimen.

Colorectal Cancer Metastatic

UNC Lineberger Comprehensive Cancer Center181 participantsStarted Apr 2011

Denver, Colorado, United States • Miami, Florida, United States • Tampa, Florida, United States +21 more locations

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

Colorectal Cancer Trials in Other Cities

A Study of OMP-305B83 in Subjects With Metastatic Colorectal Cancer

Long-term Follow-up Study Designed to Evaluate the Relative Risk of Two Colonoscopy Schedules for Patients With Small Polyps

Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers

Chemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal Cancer

A Study of Xeloda (Capecitabine) in Combination With Avastin + Short Course Chemotherapy in Patients With Metastatic Colorectal Cancer

EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options

Observational Study of Sub-populations From Cologuard Post-Approval Study (2014-01)

Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)

Sym004 vs Standard of Care in Subjects With Metastatic Colorectal Cancer

A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal Cancer

Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors

Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal Cancer

Validation of Colon Biomarkers for the Early Detection of Colorectal Adenocarcinoma

Sample Collection Study for the CellMax Life Circulating Tumor Cell and Circulating Tumor DNA Platforms for the Early Detection of Colorectal Cancer and Adenomas

Study of CS-7017 in Combination With FOLFIRI in Subjects With Metastatic Colorectal Cancer Who Failed First-Line Therapy

Safety Study of 90Y-hMN14 to Treat Colorectal Cancer

Paired Analysis of Sensitivity for Colorectal Cancer Using COLVERA : PASCAL

Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer

Other Conditions in Colorado