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Clareo Health | Colorectal Cancer Clinical Trials in Cleveland | 183 Studies

Clinical Trials Colorectal CancerCleveland

Colorectal Cancer Clinical Trials in Cleveland

Find 183 clinical trials for colorectal cancer near Cleveland, Ohio. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Cleveland

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 141-160 of 183 trials

CompletedTTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced CancersThis is a phase 1/1b study of TTX-030 in combination therapy, an antibody that inhibits CD39 enzymatic activity, leading to accumulation of pro-inflammatory adenosine triphosphate…NCT04306900·Scottsdale, Arizona and 31 others

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Data from ClinicalTrials.govTerms

Active not recruitingTesting a Combination of Vaccines for Cancer Prevention in Lynch SyndromeThis phase IIb trial tests whether Tri-Ad5 in combination with N-803 works to prevent colon and other cancers in participants with Lynch syndrome.NCT05419011·Phoenix, Arizona and 13 others

Active not recruitingA Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.The purpose of this study is to learn about the safety and effects of the study medicine alone or when given together with other anti-cancer therapies.NCT06447662·Fayetteville, Arkansas and 26 others

CompletedCombination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006786·Scottsdale, Arizona and 76 others

CompletedSurgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00023751·Anniston, Alabama and 179 others

RecruitingCollecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer DetectionThis study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.NCT05334069·Anchorage, Alaska and 750 others

CompletedPilot Study Evaluating the Efficacy of AlloMEM After Loop IleostomyThe objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.NCT01113736·Cleveland, Ohio

CompletedSurgery With or Without Radiofrequency Ablation Followed by Irinotecan in Treating Patients With Colorectal Cancer That is Metastatic to the LiverRATIONALE: Radiofrequency ablation uses high-frequency electric current to kill tumor cells. Combining radiofrequency ablation with surgery may kill more tumor cells.NCT00030563·Cleveland, Ohio and 2 others

Active not recruitingS0820, Adenoma and Second Primary Prevention TrialThe investigators hypothesize that the combination of eflornithine and sulindac will be effective in reducing a three-year event rate of adenomas and second primary colorectal…NCT01349881·Birmingham, Alabama and 988 others

RecruitingStudy of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid TumorsThis is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity…NCT05176483·Phoenix, Arizona and 121 others

TerminatedA Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and BevacizumabA study to evaluate the efficacy and tolerability of ABT-165 plus FOLFIRI compared to bevacizumab plus FOLFIRI in participants with previously treated metastatic adenocarcinoma of…NCT03368859·Chandler, Arizona and 64 others

SuspendedNatural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in CancerOne of the ways that cancer grows and spreads is by avoiding the immune system.NK cells are immune cells that kill cancer cells, but are often malfunctioning in people with…NCT05400122·Cleveland, Ohio

Not yet recruitingMindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET)The purpose of this study is to develop and test a new intervention to reduce depressive symptoms in post-treatment cancer participants.NCT06811454·Cleveland, Ohio

RecruitingStudy of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC FusionsThis is a Phase 1/2, multi-center, open-label basket study designed to evaluate the safety and anti-tumor activity of IDE196 in patients with solid tumors harboring GNAQ or GNA11…NCT03947385·Los Angeles, California and 14 others

RecruitingThe Vanguard Study: Testing a New Way to Screen for CancerThe Vanguard Study is a feasibility study to explore several aspects of evaluating multi-cancer detection (MCD) tests in a future definitive randomized controlled trial.NCT06995898·Pleasanton, California and 45 others

CompletedS1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal CancerThis randomized phase II trial studies how well irinotecan hydrochloride and cetuximab with or without vemurafenib works in treating patients with colorectal cancer that has…NCT02164916·Anchorage, Alaska and 762 others

RecruitingA Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal CancerThis randomized, multi-site, three-part study will test a new treatment called BNT314, which is designed to help the body's own defense to fight cancer in combination with another…NCT07079631·New Haven, Connecticut and 13 others

TerminatedA Study Of PF-05212384 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI In Metastatic Colorectal CancerThis is a multicenter, open label Phase 1b/2 study in patients with metastatic colorectal carcinoma.NCT01937715·Fullerton, California and 38 others

Active not recruitingTucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal CancersThis trial studies tucatinib to find out if it is safe when given with trastuzumab and other anti-cancer drugs (pembrolizumab, FOLFOX, and CAPOX).NCT04430738·Phoenix, Arizona and 26 others

CompletedCelecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous PolyposisRATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming.NCT00685568·Cleveland, Ohio and 3 others

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Other Conditions in Cleveland

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