Breast Cancer Clinical Trials

Showing 701-720 of 5,597 trials

RC48 Combined With Chemotherapy in HER2-Positive Advanced Breast Cancer Patients With Prior TOP1i-ADC Failure

NCT07366840

The purpose of this study is to assess the safety and efficacy of RC48 (a HER2 antibody drug conjugate with MMAE payload) in combination with gemcitabine or capecitabine (with or without trastuzumab/inetetamab), for treatment of patients with HER2-positive advanced breast cancer (ABC) who have developed disease progression or intolerance to prior therapy with a topoisomerase I inhibitor antibody-drug conjugate (TOP1i-ADC).

HER2-positive Breast CancerMetastatic Breast Cancer

Fudan University268 participantsStarted Jan 2026

RECRUITINGPhase 3

Corticosteroids for Doxorubicin Liposome-Induced Hand-Foot-Skin Reactions

NCT07362914

Investigating the Association Between Corticosteroid Use and Improvement in Doxorubicin Liposome-Induced Cutaneous Toxicity: Exploring the Feasibility and Mechanisms of Corticosteroids in Mitigating Liposomal Doxorubicin-Related Dermatologic Adverse Effects.

Breast Cancer

Fudan University182 participantsStarted Mar 2025

Shanghai, Shanghai Municipality, China

RECRUITINGPhase 1

F-Tryptophan PET/CT in Human Cancers

NCT05556473

Imaging procedures such as 1-(2-\[18F\]FLUOROETHYL)-L-Tryptophan PET/CT in patients with cancers may help doctors assess a patient's response to treatment and help plan the best treatment in the future. The purpose is to see if there can be a better differentiation of tumor and non-tumor tissue where the tumor tissue has a higher uptake of Tryptophan.

Intracranial GliomaMetastatic Brain TumorBreast Cancer+2 more

Barbara Ann Karmanos Cancer Institute24 participantsStarted Sep 2022

Detroit, Michigan, United States

RC48 Combined With Chemotherapy in HER2-Positive Advanced Breast Cancer Patients With Prior TOP1i-ADC Failure

Corticosteroids for Doxorubicin Liposome-Induced Hand-Foot-Skin Reactions

F-Tryptophan PET/CT in Human Cancers

Related Searches

CDK and Body Composition Study

The Effect on Attendance of an SMS Notification Prior to a Scheduled Screening Appointment in BreastScreen Norway

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET)

HKI-272 for HER2-Positive Breast Cancer and Brain Metastases

Trial to Compare MRI-guided Precision Prone Irradiation (PPI) Versus CT-guided Breast Irradiation

Study to Assess the Effect of OCT-598 in Patients With Advanced Solid Tumors

Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer

Trans-RosaLEE Study: a Biomarker-directed, Translational Study

Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer

FDA018-ADC vs Investigator's Choice Chemotherapy to Treat Locally Advanced, Recurrent or Metastatic Triple-negative Breast Cancer

Mirtazapine for Acute and Chronic Post Mastectomy Pain

Breast Cancer 2-PREVENT Translational Center of Excellence (TCE) - Metastatic Markers of Recurrent Tumor Phenotype for Breast Cancer

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

A Study of BL-M07D1 Versus T-DM1 in the Adjuvant Treatment of HER2-positive Breast Cancer With Residual Invasive Cancer After Neoadjuvant Therapy

Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy