Breast Cancer Clinical Trials

Showing 401-420 of 4,817 trials

Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer

NCT07217990

This study will evaluate the efficacy and non-inferiority of a non-surgical approach for the treatment of patients with locally advanced breast cancer.

Breast CancerHER2-positive Breast CancerTriple Negative Breast Cancer

Ohio State University Comprehensive Cancer Center84 participantsStarted Apr 2026

Columbus, Ohio, United States

Active Not RecruitingNA

Immune Tumor Stroma Factors and Pathologic Complete Response After Neoadjuvant Chemotherapy in Early Breast Cancer

NCT07407244

This prospective cohort study aims to identify immune-related predictive factors of response to neoadjuvant chemotherapy in patients with early breast cancer. The study will evaluate immune markers in tumor stroma and blood samples collected before treatment to determine their association with complete pathological remission (pCR). In addition, circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) will be analyzed to explore their correlation with treatment response. The results may contribute to improved selection of patients who are most likely to benefit from neoadjuvant chemotherapy.

Breast Cancer

Institute of Oncology Ljubljana268 participantsStarted Mar 2017

Ljubljana, Slovenia

Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer

Immune Tumor Stroma Factors and Pathologic Complete Response After Neoadjuvant Chemotherapy in Early Breast Cancer

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