Breast Cancer Clinical Trials

Showing 3141-3160 of 4,817 trials

Cancer/Testis Antigen Immunotherapy Phase I Study With 740-CTA Vaccinia Virus

NCT03110445

Monocentric open-label phase I/II trial aiming at evaluating, in adjuvant setting, safety (primary outcome), immunological and clinical efficacy (secondary outcomes) of a non replicating recombinant vaccinia virus expressing cancer/testis antigen (CTA) derived epitopes and CD80 and CD40 ligand (CD40L, CD154) costimulatory molecules in patients with CTA expressing tumors.

Breast Carcinoma

University Hospital, Basel, SwitzerlandStarted Mar 2020

COMPLETEDPhase 1

Study to Compare the Effects of AZD9496 vs Fulvestrant in Breast Cancer.

NCT03236974

This is an open label randomised multicentre pre-surgical pharmacodynamics study to compare and assess the biological effects of AZD9496 and fulvestrant in postmenopausal women with estrogen receptor (ER) positive (ER+), human epidermal growth factor receptor 2 (HER-2) negative (HER2-) primary breast cancer. Patients will receive AZD9496 or fulvestrant and will have an on-treatment image -guided core biopsy after 5-14 days of commencing treatment.

Postmenopausal Women With ER+ HER2- Primary Breast Cancer

AstraZeneca49 participantsStarted Oct 2017

Erlangen, Germany • Minden, Germany • München, Germany +9 more locations

Cancer/Testis Antigen Immunotherapy Phase I Study With 740-CTA Vaccinia Virus

Study to Compare the Effects of AZD9496 vs Fulvestrant in Breast Cancer.

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